Milbemycin

6,381 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

6,381

Total Reports

109

Deaths Reported

170.0%

Death Rate

Active Ingredients

Milbemycin

Administration Routes

OralUnknownAuricular (Otic)Topical

Species Affected

Dog 6,043

Unknown 290

Cat 33

Human 14

Other 1

Most Affected Breeds

Crossbred Canine/dog 1,422

Retriever - Labrador 1,047

Shepherd Dog - German 306

Unknown 305

Retriever - Golden 250

Beagle 155

Boxer (German Boxer) 142

Dog (unknown) 139

Dachshund (unspecified) 130

Chihuahua 98

Most Reported Reactions

INEFFECTIVE, HEARTWORM LARVAE 2,776

Vomiting 809

INEFFECTIVE, ASCARIDS NOS 749

Lack of efficacy (endoparasite) - hookworm 638

Lack of efficacy (endoparasite) - whipworm 566

Diarrhoea 561

Depression 396

Anorexia 230

Underfilling, Package 176

Convulsion 125

Ataxia 83

Pruritus 70

Outcome Breakdown

Died

104 (56.2%)

Ongoing

48 (25.9%)

Recovered/Normal

13 (7.0%)

Outcome Unknown

11 (5.9%)

Euthanized

5 (2.7%)

Recovered with Sequela

4 (2.2%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.