Drug profile
The FDA adverse-event record for Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg
5,756 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg. See the species affected, top reactions, and outcomes below.
- 5,756
- adverse-event reports
- 0.8%
- death-coded share
- Dog
- most-reported species
- 2,623
- Digestive tract disorder NOS - top reaction
Active Ingredients
Administration Routes
Species Affected
Most Affected Breeds
Most Reported Reactions
Outcome Breakdown
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg Adverse Event Insights
5,756 reports name Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg; 46 recorded a death outcome (0.8% of reported events, not a population-level mortality rate). Active ingredient: Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg. Administration routes: Oral, Unknown, Topical.
By species: Dog (5,533 reports), Unknown (217 reports), Cat (3 reports). By breed: Retriever - Labrador (1,598), Crossbred Canine/dog (607), Retriever - Golden (536).
Leading clinical signs: Digestive tract disorder NOS (2,623), INEFFECTIVE, HEARTWORM LARVAE (1,942), Cardiac disorder NOS (1,897), Lack of efficacy (endoparasite) - hookworm (1,376). Outcome, 5,556 coded reports: Outcome Unknown leads at 59.3%.
Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.
Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.