Afoxolaner 28.3 Mg Chewable Tablets
2,155 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
2,155
Total Reports
37
Deaths Reported
170.0%
Death Rate
Active Ingredients
Afoxolaner 28.3 Mg Chewable Tablets
Administration Routes
OralUnknownOther
Species Affected
Dog 1,958
Unknown 193
Human 2
Other 1
Cat 1
Most Affected Breeds
Shih Tzu 303
Crossbred Canine/dog 215
Unknown 205
Dog (unknown) 132
Lhasa Apso 131
Poodle - Miniature 93
Poodle - Toy 81
Terrier - Yorkshire 79
Maltese 69
Mixed (Dog) 61
Most Reported Reactions
Lack of efficacy (tick) 468
Skin disorders NOS 457
Vomiting 452
Lack of efficacy (flea) 301
Diarrhoea 167
Lethargy (see also Central nervous system depression in 'Neurological') 151
Pruritus 119
Lack of efficacy (ectoparasite) - NOS 86
Emesis 85
Anorexia 70
Scratching 64
Overdose 56
Outcome Breakdown
Outcome Unknown
1,226 (62.4%)
Recovered/Normal
605 (30.8%)
Ongoing
90 (4.6%)
Died
32 (1.6%)
Recovered with Sequela
6 (0.3%)
Euthanized
5 (0.3%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.