Polysulfated Glycosaminoglycan
5,558 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
5,558
Total Reports
430
Deaths Reported
770.0%
Death Rate
Active Ingredients
Polysulfated Glycosaminoglycan
Administration Routes
UnknownSubcutaneousIntramuscularParenteralIntravenousIntra-ArticularOralTopicalOphthalmicIntradermal
Species Affected
Dog 3,834
Unknown 1,000
Horse 372
Cat 303
Human 27
Other Birds 7
Other 6
Rabbit 4
Duck 1
Starling 1
Most Affected Breeds
Unknown 1,136
Retriever - Labrador 704
Dog (unknown) 319
Shepherd Dog - German 279
Retriever - Golden 224
Domestic Shorthair 168
Dog (other) 99
Boxer (German Boxer) 94
Horse (unknown) 82
Chihuahua 80
Most Reported Reactions
Vomiting 1,033
Diarrhoea 743
Product Defect, General 653
Lack of efficacy - NOS 563
Lethargy (see also Central nervous system depression in 'Neurological') 530
Not eating 366
Color, Abnormal 267
Death by euthanasia 265
Other abnormal test result NOS 237
Elevated alanine aminotransferase (ALT) 234
Anorexia 229
Weight loss 223
Outcome Breakdown
Outcome Unknown
1,740 (38.2%)
Recovered/Normal
1,508 (33.1%)
Ongoing
848 (18.6%)
Euthanized
262 (5.7%)
Died
168 (3.7%)
Recovered with Sequela
33 (0.7%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.