Betamethasone + Florfenicol + Terbinafine
2,221 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
2,221
Total Reports
38
Deaths Reported
170.0%
Death Rate
Active Ingredients
BetamethasoneFlorfenicolTerbinafine
Administration Routes
Auricular (Otic)UnknownTopicalOralIntraocularOphthalmicCutaneousOther
Species Affected
Dog 1,955
Cat 136
Unknown 115
Human 14
Other Cervids 1
Most Affected Breeds
Retriever - Labrador 296
Dog (unknown) 198
Unknown 132
Spaniel - Cocker American 110
Retriever - Golden 109
Domestic Shorthair 82
Shih Tzu 80
Shepherd Dog - German 71
Chihuahua 62
Terrier - Yorkshire 54
Most Reported Reactions
Lack of efficacy - NOS 1,128
Ear discharge 159
Loss of hearing 112
Vomiting 100
Lethargy (see also Central nervous system depression in 'Neurological') 91
Head shake - ear disorder 88
CULTURE/TITER DATA ABNORMAL 82
Deafness 80
Ear pain 75
Hearing decreased 75
Behavioural disorder NOS 73
Other abnormal test result NOS 71
Outcome Breakdown
Outcome Unknown
1,269 (60.3%)
Ongoing
484 (23.0%)
Recovered/Normal
261 (12.4%)
Recovered with Sequela
54 (2.6%)
Euthanized
21 (1.0%)
Died
17 (0.8%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.