Drug profile

The FDA adverse-event record for Betamethasone + Florfenicol + Terbinafine

2,223 FDA reports name Betamethasone + Florfenicol + Terbinafine, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#102 of 2,679
by report volume (all drugs)
2,223
adverse-event reports
1.7%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Betamethasone + Florfenicol + Terbinafine ranks #102 of 2679 by total reports (2,223) and #1012 of 1130 by death-coded share (1.7%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#102
This drug, reports of 2679
#1012
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Betamethasone + Florfenicol + Terbinafine has 2,223 reports now versus 2,223 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Betamethasone + Florfenicol + Terbinafine changes

Signature read: 2,223 reports place Betamethasone + Florfenicol + Terbinafine in the upper third of FDA AER volume (#102 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
2,223
Total Reports
38
Deaths Reported
1.7%
Death-coded share of reports

Active Ingredients

BetamethasoneFlorfenicolTerbinafine

Administration Routes

Auricular (Otic)UnknownTopicalOralIntraocularOphthalmicCutaneousOther

Species Affected

Dog 1,957
Cat 136
Unknown 115
Human 14
Other Cervids 1

Most Affected Breeds

Retriever - Labrador 296
Dog (unknown) 198
Unknown 132
Spaniel - Cocker American 110
Retriever - Golden 109
Domestic Shorthair 82
Shih Tzu 80
Shepherd Dog - German 71
Chihuahua 62
Terrier - Yorkshire 54

Most Reported Reactions

Lack of efficacy - NOS 1,129
Ear discharge 159
Loss of hearing 112
Vomiting 100
Lethargy (see also Central nervous system depression in 'Neurological') 90
Head shake - ear disorder 88
CULTURE/TITER DATA ABNORMAL 82
Deafness 80
Ear pain 75
Hearing decreased 75
Behavioural disorder NOS 73
Other abnormal test result NOS 71

Outcome Breakdown

Outcome Unknown
1,269 (60.2%)
Ongoing
485 (23.0%)
Recovered/Normal
262 (12.4%)
Recovered with Sequela
54 (2.6%)
Euthanized
21 (1.0%)
Died
17 (0.8%)

Betamethasone + Florfenicol + Terbinafine: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Betamethasone + Florfenicol + Terbinafine, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Betamethasone + Florfenicol + Terbinafine's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Betamethasone + Florfenicol + Terbinafine (#102 of 2,679 by report volume); death-coded 1.7%. PlainBreed drug row · report volume stamp 2,223 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →