Ketamine Hydrochloride
1,757 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,757
Total Reports
422
Deaths Reported
2400.0%
Death Rate
Active Ingredients
Ketamine Hydrochloride
Administration Routes
UnknownIntramuscularIntravenousIntraperitonealSubcutaneousOtherParenteralOphthalmicIntrapleuralOral
Species Affected
Cat 673
Dog 499
Horse 276
Unknown 134
Rat 34
Mouse 33
Rabbit 22
Monkey 16
Other 16
Pig 9
Most Affected Breeds
Unknown 254
Domestic Shorthair 200
Domestic (unspecified) 190
Cat (unknown) 159
Dog (unknown) 131
Horse (unknown) 97
Quarter Horse 61
Retriever - Labrador 45
Crossbred Canine/dog 42
Domestic Longhair 30
Most Reported Reactions
INEFFECTIVE, ANESTHESIA 340
Death 330
Lack of efficacy - NOS 188
INEFFECTIVE, SEDATION 185
Cardiac arrest 129
Apnoea 96
Recovery prolonged 84
Seizure NOS 81
Fever 68
Convulsion 57
Hyperthermia 53
Death by euthanasia 52
Outcome Breakdown
Recovered/Normal
621 (50.1%)
Died
367 (29.6%)
Outcome Unknown
128 (10.3%)
Ongoing
66 (5.3%)
Euthanized
55 (4.4%)
Recovered with Sequela
2 (0.2%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.