Methadone
272 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
272
Total Reports
65
Deaths Reported
2390.0%
Death Rate
Active Ingredients
Methadone
Administration Routes
UnknownIntravenousIntramuscularParenteralSubcutaneousOtherOral
Species Affected
Dog 195
Cat 73
Human 2
Deer 1
Pig 1
Most Affected Breeds
Domestic Shorthair 37
Retriever - Labrador 26
Dog (unknown) 13
Domestic Longhair 12
Retriever - Golden 11
Crossbred Canine/dog 11
Terrier - Bull - American Pit 8
Beagle 6
Boxer (German Boxer) 6
Mixed (Dog) 5
Most Reported Reactions
Lethargy (see also Central nervous system depression in Neurological) 40
Death by euthanasia 36
Not eating 36
Diarrhoea 35
Vomiting 32
Death 28
Hypotension 27
Fever 23
Tachycardia 22
Anorexia 22
Bradycardia 21
Abnormal radiograph finding 21
Outcome Breakdown
Recovered/Normal
95 (34.7%)
Ongoing
66 (24.1%)
Outcome Unknown
46 (16.8%)
Euthanized
35 (12.8%)
Died
30 (10.9%)
Recovered with Sequela
2 (0.7%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.