Imidacloprid, Moxidectin
1,792 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,792
Total Reports
74
Deaths Reported
410.0%
Death Rate
Active Ingredients
Imidacloprid, Moxidectin
Administration Routes
TopicalUnknownOtherOralIntraocularOphthalmicNasalIntrauterineRespiratory (Inhalation)Subcutaneous
Species Affected
Dog 1,110
Cat 583
Unknown 48
Human 48
Guinea Pig 1
Rabbit 1
Other 1
Most Affected Breeds
Domestic (unspecified) 390
Crossbred Canine/dog 174
Retriever - Labrador 107
Dog (unknown) 103
Cat (unknown) 99
Unknown 98
Chihuahua 57
Terrier - Yorkshire 54
Shepherd Dog - German 46
Domestic Shorthair 43
Most Reported Reactions
Depression 269
Vomiting 249
Lack of efficacy (endoparasite) - heartworm 178
Hypersalivation 177
Anorexia 139
Behavioural disorder NOS 121
Ataxia 114
Hyperactivity 111
Application site alopecia 108
Accidental exposure 107
Trembling 106
Lack of efficacy (ectoparasite) - flea 104
Outcome Breakdown
Outcome Unknown
391 (60.2%)
Ongoing
119 (18.3%)
Recovered/Normal
66 (10.2%)
Died
62 (9.5%)
Euthanized
12 (1.8%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.