Ivermectin, Pyrantel Pamoate
219 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
219
Total Reports
12
Deaths Reported
550.0%
Death Rate
Active Ingredients
Ivermectin, Pyrantel Pamoate
Administration Routes
OralUnknown
Species Affected
Dog 217
Unknown 2
Most Affected Breeds
Retriever - Labrador 41
Shepherd Dog - German 12
Crossbred Canine/dog 11
Dog (unknown) 11
Boxer (German Boxer) 9
Terrier - Bull - American Pit 8
Terrier (unspecified) 7
Shih Tzu 6
Chihuahua 5
Beagle 5
Most Reported Reactions
Lack of efficacy (endoparasite) - heartworm 70
INEFFECTIVE, HEARTWORM LARVAE 51
Lack of efficacy - NOS 35
Lethargy (see also Central nervous system depression in 'Neurological') 21
Vomiting 19
Diarrhoea 17
Seizure NOS 11
Ataxia 8
Death 7
Anorexia 5
Death by euthanasia 5
Panting 5
Outcome Breakdown
Ongoing
136 (62.7%)
Outcome Unknown
40 (18.4%)
Recovered/Normal
29 (13.4%)
Died
7 (3.2%)
Euthanized
5 (2.3%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.