Drug profile

The FDA adverse-event record for Flumethrin,Imidacloprid

123 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Flumethrin,Imidacloprid. See the species affected, top reactions, and outcomes below.

123
adverse-event reports
1.6%
death-coded share
Dog
most-reported species
33
Lack of efficacy (ectoparasite) - flea - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
123
Total Reports
2
Deaths Reported
1.6%
Death Rate

Active Ingredients

Flumethrin,Imidacloprid

Administration Routes

TopicalUnknown

Species Affected

Dog 112
Cat 10
Unknown 1

Most Affected Breeds

Retriever - Labrador 13
Retriever - Golden 8
Pit Bull 6
Dog (unknown) 6
Shepherd Dog - Australian 5
Shih Tzu 5
Chihuahua 4
Shepherd Dog - German 4
Schnauzer - Miniature 3
Spaniel - Cocker American 3

Most Reported Reactions

Lack of efficacy (ectoparasite) - flea 33
Lethargy (see also Central nervous system depression in Neurological) 17
Lack of efficacy (ectoparasite) - tick NOS 15
Vomiting 12
Behavioural disorder NOS 12
Pruritus 9
Itching 8
Other abnormal test result NOS 8
Lack of efficacy (endoparasite) - tapeworm 8
Lack of efficacy (bacteria) - Borrelia 8
Lack of efficacy (endoparasite) - heartworm 8
Scratching 8

Outcome Breakdown

Outcome Unknown
67 (54.9%)
Ongoing
35 (28.7%)
Recovered/Normal
18 (14.8%)
Euthanized
1 (0.8%)
Died
1 (0.8%)

Flumethrin,Imidacloprid Adverse Event Insights

123 reports name Flumethrin,Imidacloprid; 2 recorded a death outcome (1.6% of reported events, not a population-level mortality rate). Active ingredient: Flumethrin,Imidacloprid. Administration routes: Topical, Unknown.

By species: Dog (112 reports), Cat (10 reports), Unknown (1 reports). By breed: Retriever - Labrador (13), Retriever - Golden (8), Pit Bull (6).

Leading clinical signs: Lack of efficacy (ectoparasite) - flea (33), Lethargy (see also Central nervous system depression in Neurological) (17), Lack of efficacy (ectoparasite) - tick NOS (15), Vomiting (12). Outcome, 122 coded reports: Outcome Unknown leads at 54.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.