Drug profile

The FDA adverse-event record for Nutraceutical Joint Supplement

73 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Nutraceutical Joint Supplement. Species, reactions, and outcomes follow.

#918 of 2,679
by report volume (all drugs)
73
adverse-event reports
5.5%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Nutraceutical Joint Supplement ranks #914 of 2679 by total reports (73) and #761 of 1130 by death-coded share (5.5%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#914
This drug, reports of 2679
#761
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Nutraceutical Joint Supplement has 73 reports now versus 70 in that prior snapshot: 3 more (4.3%).

Report change
+3
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Nutraceutical Joint Supplement changes

Signature read: Nutraceutical Joint Supplement's 5.5% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
73
Total Reports
4
Deaths Reported
5.5%
Death-coded share of reports

Active Ingredients

Nutraceutical Joint Supplement

Administration Routes

UnknownOralOther

Species Affected

Dog 65
Cat 8

Most Affected Breeds

Retriever - Labrador 23
Domestic Shorthair 5
Crossbred Canine/dog 4
Collie - Border 3
Retriever - Golden 3
Spitz - German Pomeranian 3
Dog (unknown) 3
Beagle 3
Spaniel - Cocker English 2
Shepherd Dog - German 2

Most Reported Reactions

Diarrhoea 14
Vomiting 11
Anorexia 7
Abnormal radiograph finding 7
Not eating 6
Lack of efficacy - NOS 6
Decreased appetite 5
Lack of efficacy (endoparasite) - roundworm NOS 5
Lethargy (see also Central nervous system depression in Neurological) 5
Nausea 4
Anaemia NOS 4
Weakness 4

Outcome Breakdown

Ongoing
29 (39.7%)
Outcome Unknown
27 (37.0%)
Recovered/Normal
13 (17.8%)
Died
2 (2.7%)
Euthanized
2 (2.7%)

Nutraceutical Joint Supplement: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Nutraceutical Joint Supplement, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (73 here).

Similar death-coded share

Nearest other drugs by death-coded share (5.5% here), distinct from the volume row.

What to do with this drug

  • Compare Nutraceutical Joint Supplement's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Nutraceutical Joint Supplement (#918 of 2,679 by report volume); death-coded 5.5%. PlainBreed drug row · death-coded share stamp 5.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →