Drug profile

The FDA adverse-event record for Bravecto

216 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bravecto. See the species affected, top reactions, and outcomes below.

216
adverse-event reports
9.7%
death-coded share
Dog
most-reported species
27
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
216
Total Reports
21
Deaths Reported
9.7%
Death Rate

Active Ingredients

Bravecto

Administration Routes

UnknownOralTopicalSubcutaneous

Species Affected

Dog 192
Cat 24

Most Affected Breeds

Retriever - Labrador 27
Domestic Shorthair 17
Retriever - Golden 16
Crossbred Canine/dog 12
Terrier - Bull - American Pit 12
Boxer (German Boxer) 9
Bulldog - French 9
Shepherd Dog - German 8
Terrier (unspecified) 6
Shepherd Dog - Australian 5

Most Reported Reactions

Vomiting 27
Seizure NOS 24
Lack of efficacy - NOS 23
Diarrhoea 15
Ataxia 15
Not eating 12
Elevated serum alkaline phosphatase (ALP) 12
Intentional misuse 12
Lethargy (see also Central nervous system depression in Neurological) 11
Death 10
Lethargy (see also Central nervous system depression in 'Neurological') 10
Death by euthanasia 10

Outcome Breakdown

Ongoing
141 (65.3%)
Recovered/Normal
33 (15.3%)
Outcome Unknown
21 (9.7%)
Died
11 (5.1%)
Euthanized
10 (4.6%)

Bravecto Adverse Event Insights

216 reports name Bravecto; 21 recorded a death outcome (9.7% of reported events, not a population-level mortality rate). Active ingredient: Bravecto. Administration routes: Unknown, Oral, Topical, Subcutaneous.

By species: Dog (192 reports), Cat (24 reports). By breed: Retriever - Labrador (27), Domestic Shorthair (17), Retriever - Golden (16).

Leading clinical signs: Vomiting (27), Seizure NOS (24), Lack of efficacy - NOS (23), Diarrhoea (15). Outcome, 216 coded reports: Ongoing leads at 65.3%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.