Thiabendazole + Dexamethasone + Neomycin

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139 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
139
Total Reports
8
Deaths Reported
580.0%
Death Rate

Active Ingredients

Thiabendazole + Dexamethasone + Neomycin

Administration Routes

Auricular (Otic)UnknownTopicalOral

Species Affected

Dog 85
Cat 53
Ferret 1

Most Affected Breeds

Domestic Shorthair 28
Retriever - Golden 7
Domestic Longhair 7
Maltese 6
Pug 6
Chihuahua 5
Boxer (German Boxer) 4
Shih Tzu 4
Pit Bull 4
Foxhound - American 4

Most Reported Reactions

Emesis 31
Vomiting 21
Lethargy (see also Central nervous system depression in 'Neurological') 20
Behavioural disorder NOS 14
Lack of efficacy - NOS 12
Lethargy (see also Central nervous system depression in Neurological) 11
Other abnormal test result NOS 10
Ear infection NOS 10
Decreased appetite 9
Not eating 8
Diarrhoea 7
Ataxia 7

Outcome Breakdown

Recovered/Normal
60 (43.2%)
Outcome Unknown
34 (24.5%)
Ongoing
34 (24.5%)
Died
6 (4.3%)
Recovered with Sequela
3 (2.2%)
Euthanized
2 (1.4%)

Data Summary

Metric Value
Total adverse event reports 139
Reports involving death 8
Case-fatality rate (reported events) 580.0%
Distinct species in reports 3
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Thiabendazole + Dexamethasone + Neomycin Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 139 adverse event reports referencing Thiabendazole + Dexamethasone + Neomycin, including 8 reports in which the animal died — a 580.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Thiabendazole + Dexamethasone + Neomycin. Reported administration routes include Auricular (Otic), Unknown, Topical, Oral. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Thiabendazole + Dexamethasone + Neomycin reports are Dog (85 reports), Cat (53 reports), Ferret (1 reports), with Dog accounting for the largest share. Within those species, Domestic Shorthair (28), Retriever - Golden (7), Domestic Longhair (7) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Thiabendazole + Dexamethasone + Neomycin are Emesis (31), Vomiting (21), Lethargy (see also Central nervous system depression in 'Neurological') (20), Behavioural disorder NOS (14). Of the 139 reports with a coded outcome, Recovered/Normal is the leading category at 43.2%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Thiabendazole + Dexamethasone + Neomycin.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial