Ivermectin + Pyrantel As Pamoate Salt

90,788 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

90,788

Total Reports

1,834

Deaths Reported

200.0%

Death Rate

Active Ingredients

IvermectinPyrantel As Pamoate Salt

Administration Routes

OralUnknownOtherTopicalSubcutaneousTransplacentalParenteralIntramuscularPerineuralAuricular (Otic)

Species Affected

Dog 82,476

Unknown 8,264

Human 19

Cat 15

Other Canids 5

Macaw 4

Wolf 2

Fox 1

Goat 1

Other 1

Most Affected Breeds

Retriever - Labrador 14,668

Unknown 8,337

Crossbred Canine/dog 5,910

Shepherd Dog - German 4,912

Retriever - Golden 4,645

Dog (unknown) 3,497

Beagle 2,805

Pit Bull 2,672

Chihuahua 1,943

Boxer (German Boxer) 1,843

Most Reported Reactions

Lack of efficacy (endoparasite) - heartworm 18,221

Lack of efficacy (endoparasite) - hookworm 13,580

Digestive tract disorder NOS 13,024

INEFFECTIVE, HEARTWORM LARVAE 11,970

Vomiting 9,752

Cardiac disorder NOS 6,766

INEFFECTIVE, HOOKS 6,534

Lack of efficacy - NOS 5,441

Lack of efficacy (endoparasite) - roundworm NOS 4,626

Tablets, Abnormal 4,498

Diarrhoea 4,361

INEFFECTIVE, ASCARIDS NOS 4,258

Outcome Breakdown

Outcome Unknown

46,613 (56.5%)

Recovered with Sequela

14,093 (17.1%)

Recovered/Normal

12,180 (14.8%)

Ongoing

7,828 (9.5%)

Died

1,165 (1.4%)

Euthanized

671 (0.8%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.