Spinosad

66,270 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

66,270

Total Reports

1,648

Deaths Reported

250.0%

Death Rate

Active Ingredients

Spinosad

Administration Routes

OralUnknownCutaneousTopicalOtherRespiratory (Inhalation)IntraocularRectalIntrauterineOphthalmic

Species Affected

Dog 50,664

Cat 11,650

Unknown 3,771

Human 168

Other 8

Other Canids 6

Macaw 1

Crustacea 1

Cattle 1

Most Affected Breeds

Domestic Shorthair 6,477

Crossbred Canine/dog 4,539

Unknown 3,959

Chihuahua 3,541

Retriever - Labrador 2,959

Dog (unknown) 2,958

Terrier - Yorkshire 2,768

Shih Tzu 2,426

Pit Bull 1,395

Boxer (German Boxer) 1,380

Most Reported Reactions

Emesis 19,053

Vomiting 17,208

Lack of efficacy (ectoparasite) - flea 12,856

Lethargy (see also Central nervous system depression in 'Neurological') 5,205

UNPALATABLE 4,874

Lack of efficacy - NOS 2,530

Diarrhoea 2,071

Depression 1,948

Pruritus 1,717

Anorexia 1,559

Behavioural disorder NOS 1,364

Seizure NOS 1,303

Outcome Breakdown

Recovered/Normal

29,379 (59.2%)

Outcome Unknown

13,595 (27.4%)

Recovered with Sequela

3,197 (6.4%)

Ongoing

1,780 (3.6%)

Died

1,223 (2.5%)

Euthanized

427 (0.9%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.