Drug profile

The FDA adverse-event record for Dietary Supplement

97 FDA reports name Dietary Supplement, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#792 of 2,679
by report volume (all drugs)
97
adverse-event reports
2.1%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Dietary Supplement ranks #791 of 2679 by total reports (97) and #980 of 1130 by death-coded share (2.1%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#791
This drug, reports of 2679
#980
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Dietary Supplement has 97 reports now versus 95 in that prior snapshot: 2 more (2.1%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Dietary Supplement changes

Signature read: Dietary Supplement's 2.1% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
97
Total Reports
2
Deaths Reported
2.1%
Death-coded share of reports

Active Ingredients

Dietary Supplement

Administration Routes

UnknownOral

Species Affected

Dog 49
Cat 47
Human 1

Most Affected Breeds

Domestic Shorthair 28
Crossbred Canine/dog 7
Bulldog - French 7
Domestic Longhair 5
Retriever - Labrador 5
Shepherd Dog - German 4
Dog (unknown) 4
Cat (unknown) 4
Domestic Mediumhair 4
Mixed (Dog) 2

Most Reported Reactions

Vomiting 29
Ketosis 21
Diarrhoea 17
Hyperglycaemia 14
Polyuria 13
Lack of efficacy - NOS 12
Polydipsia 12
Lethargy (see also Central nervous system depression in Neurological) 12
Weight loss 10
Other abnormal test result NOS 9
Behavioural disorder NOS 8
Not eating 7

Outcome Breakdown

Ongoing
36 (37.1%)
Outcome Unknown
35 (36.1%)
Recovered/Normal
24 (24.7%)
Died
1 (1.0%)
Euthanized
1 (1.0%)

Dietary Supplement: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Dietary Supplement, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Dietary Supplement (#792 of 2,679 by report volume); death-coded 2.1%. PlainBreed drug row · death-coded share stamp 2.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →