Moxidectin

44,551 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

44,551

Total Reports

1,597

Deaths Reported

360.0%

Death Rate

Active Ingredients

Moxidectin

Administration Routes

SubcutaneousUnknownTopicalParenteralOralOtherSubconjunctivalIntramuscularOphthalmicIntradermal

Species Affected

Dog 40,349

Unknown 2,984

Cattle 774

Human 184

Horse 139

Goat 48

Sheep 40

Cat 8

Donkey 5

Other 4

Most Affected Breeds

Retriever - Labrador 5,493

Unknown 3,191

Terrier - Bull - American Pit 2,705

Crossbred Canine/dog 1,983

Chihuahua 1,700

Shepherd Dog - German 1,655

Retriever - Golden 1,503

Boxer (German Boxer) 1,423

Terrier - Yorkshire 1,147

Dog (unknown) 1,029

Most Reported Reactions

Lack of efficacy (endoparasite) - heartworm 8,728

Vomiting 8,121

Lack of efficacy (endoparasite) - hookworm 3,791

Lethargy (see also Central nervous system depression in 'Neurological') 3,738

Facial swelling (see also 'Skin') 3,671

Anaphylaxis 2,931

Hives (see also 'Skin') 2,675

Diarrhoea 2,544

Lack of efficacy (endoparasite) - roundworm NOS 1,717

Lack of efficacy (endoparasite) - NOS 1,697

INEFFECTIVE, HEARTWORM LARVAE 1,663

Pale mucous membrane 1,531

Outcome Breakdown

Ongoing

28,168 (69.2%)

Recovered/Normal

7,935 (19.5%)

Outcome Unknown

2,930 (7.2%)

Died

1,105 (2.7%)

Euthanized

505 (1.2%)

Recovered with Sequela

38 (0.1%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.