Isoflurane

4,251 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

4,251

Total Reports

794

Deaths Reported

1870.0%

Death Rate

Active Ingredients

Isoflurane

Administration Routes

Respiratory (Inhalation)UnknownOtherIntravenousNasalEndotrachealTopicalOralParenteralOphthalmic

Species Affected

Dog 2,226

Cat 1,693

Human 69

Unknown 58

Other 46

Rabbit 36

Horse 35

Mouse 16

Guinea Pig 11

Other Birds 10

Most Affected Breeds

Domestic Shorthair 968

Unknown 300

Retriever - Labrador 260

Dog (unknown) 208

Cat (unknown) 196

Domestic Longhair 130

Chihuahua 97

Crossbred Canine/dog 88

Retriever - Golden 82

Domestic Mediumhair 72

Most Reported Reactions

Death 558

Vomiting 372

Bradycardia 333

Lethargy (see also Central nervous system depression in 'Neurological') 331

Anorexia 306

Cardiac arrest 304

Not eating 262

INEFFECTIVE, ANESTHESIA 248

Behavioural disorder NOS 248

Lack of efficacy - NOS 225

Other abnormal test result NOS 217

Hypothermia 210

Outcome Breakdown

Recovered/Normal

1,571 (38.7%)

Ongoing

979 (24.1%)

Outcome Unknown

667 (16.4%)

Died

604 (14.9%)

Euthanized

197 (4.8%)

Recovered with Sequela

45 (1.1%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.