Drug profile

The FDA adverse-event record for Deracoxib

4,238 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Deracoxib. See the species affected, top reactions, and outcomes below.

4,238
adverse-event reports
17.6%
death-coded share
Dog
most-reported species
986
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
4,238
Total Reports
744
Deaths Reported
17.6%
Death Rate

Active Ingredients

Deracoxib

Administration Routes

OralUnknownOphthalmicVaginalOtherCutaneousIntragastric

Species Affected

Dog 3,657
Unknown 568
Cat 8
Human 3
Other Canids 1
Horse 1

Most Affected Breeds

Retriever - Labrador 909
Unknown 576
Crossbred Canine/dog 300
Retriever - Golden 219
Shepherd Dog - German 165
Dog (unknown) 131
Rottweiler 127
Boxer (German Boxer) 120
Pit Bull 79
Shepherd Dog - Australian 73

Most Reported Reactions

Vomiting 986
Anorexia 723
Other abnormal test result NOS 707
Lethargy (see also Central nervous system depression in 'Neurological') 541
Elevated blood urea nitrogen (BUN) 504
Tablets, Abnormal 500
Diarrhoea 495
Elevated creatinine 447
Death by euthanasia 416
Depression 376
Elevated serum alkaline phosphatase (SAP) 361
Elevated alanine aminotransferase (ALT) 321

Outcome Breakdown

Ongoing
831 (28.0%)
Recovered/Normal
686 (23.2%)
Outcome Unknown
637 (21.5%)
Died
434 (14.6%)
Euthanized
310 (10.5%)
Recovered with Sequela
65 (2.2%)

Deracoxib Adverse Event Insights

4,238 reports name Deracoxib; 744 recorded a death outcome (17.6% of reported events, not a population-level mortality rate). Active ingredient: Deracoxib. Administration routes: Oral, Unknown, Ophthalmic, Vaginal.

By species: Dog (3,657 reports), Unknown (568 reports), Cat (8 reports). By breed: Retriever - Labrador (909), Unknown (576), Crossbred Canine/dog (300).

Leading clinical signs: Vomiting (986), Anorexia (723), Other abnormal test result NOS (707), Lethargy (see also Central nervous system depression in 'Neurological') (541). Outcome, 2,963 coded reports: Ongoing leads at 28.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.