Drug profile

The FDA adverse-event record for Deracoxib

4,292 FDA reports name Deracoxib, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#53 of 2,679
by report volume (all drugs)
4,292
adverse-event reports
17.5%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Deracoxib ranks #53 of 2679 by total reports (4,292) and #287 of 1130 by death-coded share (17.5%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#53
This drug, reports of 2679
#287
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Deracoxib has 4,292 reports now versus 4,268 in that prior snapshot: 24 more (0.6%).

Report change
+24
Death-coded reports
+4
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Deracoxib changes

Signature read: death-coded report count at 750 is the most distinctive stamp on Deracoxib's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
4,292
Total Reports
750
Deaths Reported
17.5%
Death-coded share of reports

Active Ingredients

Deracoxib

Administration Routes

OralUnknownOphthalmicVaginalOtherCutaneousIntragastric

Species Affected

Dog 3,708
Unknown 571
Cat 8
Human 3
Other Canids 1
Horse 1

Most Affected Breeds

Retriever - Labrador 923
Unknown 579
Crossbred Canine/dog 302
Retriever - Golden 222
Shepherd Dog - German 166
Dog (unknown) 132
Rottweiler 127
Boxer (German Boxer) 122
Pit Bull 79
Shepherd Dog - Australian 73

Most Reported Reactions

Vomiting 990
Anorexia 723
Other abnormal test result NOS 712
Lethargy (see also Central nervous system depression in 'Neurological') 541
Elevated blood urea nitrogen (BUN) 506
Tablets, Abnormal 503
Diarrhoea 500
Elevated creatinine 448
Death by euthanasia 422
Depression 376
Elevated serum alkaline phosphatase (SAP) 361
Elevated alanine aminotransferase (ALT) 324

Outcome Breakdown

Ongoing
857 (28.4%)
Recovered/Normal
693 (23.0%)
Outcome Unknown
649 (21.5%)
Died
434 (14.4%)
Euthanized
316 (10.5%)
Recovered with Sequela
65 (2.2%)

Deracoxib: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Deracoxib, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Deracoxib (#53 of 2,679 by report volume); death-coded 17.5%. PlainBreed drug row · death-coded report count stamp 750 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →