Milbemycin/Lufenuron/Pzq Chew
4,022 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
4,022
Total Reports
64
Deaths Reported
160.0%
Death Rate
Active Ingredients
Milbemycin/Lufenuron/Pzq Chew
Administration Routes
OralUnknownDentalOculonasal
Species Affected
Dog 3,934
Unknown 88
Most Affected Breeds
Crossbred Canine/dog 1,084
Retriever - Labrador 430
Shepherd Dog - German 191
Retriever - Golden 186
Dog (unknown) 128
Pit Bull 110
Shepherd Dog - Australian 97
Beagle 93
Unknown 89
Chihuahua 78
Most Reported Reactions
Lack of efficacy (endoparasite) - heartworm 1,316
Lack of efficacy (endoparasite) - hookworm 630
Vomiting 448
Lack of efficacy (endoparasite) - roundworm NOS 340
Lack of efficacy (ectoparasite) - flea 214
Emesis (multiple) 208
Lack of efficacy (endoparasite) - tapeworm 162
Diarrhoea 155
Drug dose omission 131
Lack of efficacy (endoparasite) - whipworm 121
Lethargy (see also Central nervous system depression in Neurological) 101
Seizure NOS 90
Outcome Breakdown
Ongoing
2,854 (72.5%)
Recovered/Normal
867 (22.0%)
Outcome Unknown
121 (3.1%)
Died
32 (0.8%)
Euthanized
32 (0.8%)
Recovered with Sequela
29 (0.7%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.