Drug profile

The FDA adverse-event record for Hydrolyzed Protein Diet

118 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Hydrolyzed Protein Diet. See the species affected, top reactions, and outcomes below.

118
adverse-event reports
8.5%
death-coded share
Dog
most-reported species
28
Diarrhoea - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
118
Total Reports
10
Deaths Reported
8.5%
Death Rate

Active Ingredients

Hydrolyzed Protein Diet

Administration Routes

UnknownOral

Species Affected

Dog 84
Cat 34

Most Affected Breeds

Domestic Shorthair 25
Retriever - Golden 7
Terrier - Yorkshire 6
Retriever - Labrador 6
Domestic Longhair 5
Bulldog - French 5
Bulldog 4
Bulldog - English 4
Shepherd Dog - German 4
Crossbred Canine/dog 3

Most Reported Reactions

Diarrhoea 28
Lethargy (see also Central nervous system depression in Neurological) 27
Vomiting 21
Weight loss 17
Lack of efficacy - NOS 17
Not eating 16
Decreased appetite 10
Elevated alanine aminotransferase (ALT) 9
Pruritus 9
Loose stool 8
Abnormal cytology 8
Behavioural disorder NOS 8

Outcome Breakdown

Ongoing
60 (50.8%)
Outcome Unknown
37 (31.4%)
Recovered/Normal
11 (9.3%)
Euthanized
8 (6.8%)
Died
2 (1.7%)

Hydrolyzed Protein Diet Adverse Event Insights

118 reports name Hydrolyzed Protein Diet; 10 recorded a death outcome (8.5% of reported events, not a population-level mortality rate). Active ingredient: Hydrolyzed Protein Diet. Administration routes: Unknown, Oral.

By species: Dog (84 reports), Cat (34 reports). By breed: Domestic Shorthair (25), Retriever - Golden (7), Terrier - Yorkshire (6).

Leading clinical signs: Diarrhoea (28), Lethargy (see also Central nervous system depression in Neurological) (27), Vomiting (21), Weight loss (17). Outcome, 118 coded reports: Ongoing leads at 50.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.