Drug profile

The FDA adverse-event record for Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, [Usp] + Triamcinolone Acetonide, Usp

Name: Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, [Usp] + Triamcinolone Acetonide, Usp - FDA Animal Adverse Event Reports
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

152 FDA reports name Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, [Usp] + Triamcinolone Acetonide, Usp, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#626 of 2,679
by report volume (all drugs): 152
adverse-event reports: 1.3%
death-coded share: Dog
most-reported species

Compiled by PlainBreed

Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, [Usp] + Triamcinolone Acetonide, Usp ranks #625 of 2679 by total reports (152) and #1046 of 1130 by death-coded share (1.3%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1): 97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1): #625
This drug, reports of 2679: #1046
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, [Usp] + Triamcinolone Acetonide, Usp has 152 reports now versus 152 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: −0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, [Usp] + Triamcinolone Acetonide, Usp changes

Signature read: Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, [Usp] + Triamcinolone Acetonide, Usp's 1.3% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

152

Total Reports

Deaths Reported

1.3%

Death-coded share of reports

Active Ingredients

Neomycin Sulfate, UspNystatin, UspThiostrepton, [Usp]Triamcinolone Acetonide, Usp

Administration Routes

Auricular (Otic)UnknownTopicalTransdermal

Species Affected

Dog 136

Cat 10

Unknown 5

Other Birds 1

Most Affected Breeds

Unknown 22

Terrier - Yorkshire 11

Retriever - Labrador 9

Shih Tzu 8

Bichon Frise 6

Shepherd Dog - German 5

Chihuahua 5

Maltese 4

Domestic Shorthair 4

Mixed (Dog) 4

Most Reported Reactions

Deafness 61

Temporary deafness 49

PR-EAR(S), LESION(S) 41

Vomiting 6

Loss of hearing 4

Unclassifiable adverse event 4

Indigestion 4

Tubes, Leaking 3

Caps, Abnormal 2

Partial deafness 2

Hearing decreased 2

Death 2

Outcome Breakdown

Ongoing

58 (39.7%)

Recovered/Normal

47 (32.2%)

Outcome Unknown

37 (25.3%)

Recovered with Sequela

2 (1.4%)

Died

2 (1.4%)

Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, [Usp] + Triamcinolone Acetonide, Usp: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, [Usp] + Triamcinolone Acetonide, Usp, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (152 here).

Hydrolyzed Protein Diet 152 Bupivacaine Lipsome Injectable Suspension 153 Canine Adenovirus Type 2-Parainfluenza-Bordetella Bronchiseptica Vaccine, Modified Live Virus, Avirulent Live Culture 153 Decoquinate 153

Similar death-coded share

Nearest other drugs by death-coded share (1.3% here), distinct from the volume row.

Flea Shampoo 1.3% Ivermectin 136Mcg, Pyrantel 114Mg 1.3% Imepitoin 1.3% Milbemycin Oxime, Lufenuron, Praziquantel 1.3%

What to do with this drug

Compare Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, [Usp] + Triamcinolone Acetonide, Usp's report volume and death-coded share against similar drugs nationwide. See similar drugs
Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Neomycin Sulfate, Usp + Nystatin, Usp + Thiostrepton, [Usp] + Triamcinolone Acetonide, Usp (#626 of 2,679 by report volume); death-coded 1.3%. PlainBreed drug row · death-coded share stamp 1.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →