Drug profile

The FDA adverse-event record for Decoquinate

153 FDA reports name Decoquinate, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#623 of 2,679
by report volume (all drugs)
153
adverse-event reports
24.2%
death-coded share
Cattle
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Decoquinate ranks #621 of 2679 by total reports (153) and #183 of 1130 by death-coded share (24.2%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#621
This drug, reports of 2679
#183
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Decoquinate has 153 reports now versus 153 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Decoquinate changes

Signature read: death-coded report count at 37 is the most distinctive stamp on Decoquinate's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
153
Total Reports
37
Deaths Reported
24.2%
Death-coded share of reports

Active Ingredients

Decoquinate

Administration Routes

OralUnknown

Species Affected

Cattle 97
Unknown 30
Goat 7
Sheep 7
Chicken 4
Horse 3
Other Birds 2
Dog 2
Cat 1

Most Affected Breeds

Unknown 30
Holstein-Friesian also known as Holstein 26
Cattle (other) 26
Mixed (Cattle) 26
Sheep (unknown) 7
Jersey 7
Cattle (unknown) 5
Goat (unknown) 5
Aberdeen Angus 4
Chicken (unknown) 3

Most Reported Reactions

Lack of efficacy (protozoa) - Coccidia 38
INEFFECTIVE, COCCIDIA 32
Death 27
No sign 21
Hard, clumping 18
Lack of efficacy - NOS 17
Device Defective NOS 8
Seal, Abnormal 5
Overdose 5
Sudden death 4
Underdose 4
Accidental exposure 3

Outcome Breakdown

Outcome Unknown
85 (57.4%)
Died
37 (25.0%)
Recovered/Normal
13 (8.8%)
Ongoing
12 (8.1%)
Euthanized
1 (0.7%)

Decoquinate: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Decoquinate, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Decoquinate (#623 of 2,679 by report volume); death-coded 24.2%. PlainBreed drug row · death-coded report count stamp 37 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →