Drug profile

The FDA adverse-event record for Ivermectin(1%)/Clorsulon(10%) Injection

304 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Ivermectin(1%)/Clorsulon(10%) Injection. See the species affected, top reactions, and outcomes below.

304
adverse-event reports
7.9%
death-coded share
Unknown
most-reported species
123
Uncoded sign - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
304
Total Reports
24
Deaths Reported
7.9%
Death Rate

Active Ingredients

Ivermectin(1%)/Clorsulon(10%) Injection

Administration Routes

UnknownSubcutaneousOralIntramuscularIntradermalOphthalmicTopicalParenteral

Species Affected

Unknown 200
Cattle 69
Dog 20
Human 8
Horse 3
Cat 1
Other Birds 1
Sheep 1
Hedgehog 1

Most Affected Breeds

Unknown 212
Cattle (unknown) 24
Crossbred Bovine/Cattle 11
Cattle (other) 9
Aberdeen Angus 8
Holstein-Friesian also known as Holstein 5
Retriever - Labrador 4
Standardbred (unspecified) 3
Dog (unknown) 3
Collie - Border 2

Most Reported Reactions

Uncoded sign 123
Caps, Abnormal 98
Stopper, abnormal 54
Closure, Abnormal 20
Death 17
Ataxia 11
Systemic disorder NOS 11
Digestive tract disorder NOS 9
Vomiting 8
Mydriasis 8
Seal, Abnormal 7
Lack of efficacy (endoparasite) - trematode 7

Outcome Breakdown

Outcome Unknown
69 (59.5%)
Died
20 (17.2%)
Recovered/Normal
15 (12.9%)
Ongoing
7 (6.0%)
Euthanized
5 (4.3%)

Ivermectin(1%)/Clorsulon(10%) Injection Adverse Event Insights

304 reports name Ivermectin(1%)/Clorsulon(10%) Injection; 24 recorded a death outcome (7.9% of reported events, not a population-level mortality rate). Active ingredient: Ivermectin(1%)/Clorsulon(10%) Injection. Administration routes: Unknown, Subcutaneous, Oral, Intramuscular.

By species: Unknown (200 reports), Cattle (69 reports), Dog (20 reports). By breed: Unknown (212), Cattle (unknown) (24), Crossbred Bovine/Cattle (11).

Leading clinical signs: Uncoded sign (123), Caps, Abnormal (98), Stopper, abnormal (54), Closure, Abnormal (20). Outcome, 116 coded reports: Outcome Unknown leads at 59.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.