Drug profile

The FDA adverse-event record for Hypoallergenic Diet (Unknown)

153 FDA reports name Hypoallergenic Diet (Unknown), a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#624 of 2,679
by report volume (all drugs)
153
adverse-event reports
2.6%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Hypoallergenic Diet (Unknown) ranks #621 of 2679 by total reports (153) and #944 of 1130 by death-coded share (2.6%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#621
This drug, reports of 2679
#944
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hypoallergenic Diet (Unknown) has 153 reports now versus 148 in that prior snapshot: 5 more (3.4%).

Report change
+5
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hypoallergenic Diet (Unknown) changes

Signature read: Hypoallergenic Diet (Unknown)'s 2.6% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
153
Total Reports
4
Deaths Reported
2.6%
Death-coded share of reports

Active Ingredients

Hypoallergenic Diet (Unknown)

Administration Routes

UnknownOralIntraocular

Species Affected

Dog 116
Cat 37

Most Affected Breeds

Domestic Shorthair 24
Retriever - Labrador 9
Shih Tzu 7
Boxer (German Boxer) 6
Domestic Longhair 6
Shepherd Dog - German 6
Crossbred Canine/dog 5
Maltese 5
Terrier - Jack Russell 4
Pit Bull 4

Most Reported Reactions

Emesis 32
Vomiting 32
Lack of efficacy - NOS 26
Diarrhoea 17
Behavioural disorder NOS 11
Other abnormal test result NOS 10
Lethargy (see also Central nervous system depression in 'Neurological') 10
Weight loss 10
Lack of efficacy (ectoparasite) - flea 7
Neutropenia 7
Itching 6
Anorexia 6

Outcome Breakdown

Outcome Unknown
55 (35.9%)
Recovered/Normal
53 (34.6%)
Ongoing
31 (20.3%)
Recovered with Sequela
10 (6.5%)
Euthanized
4 (2.6%)

Hypoallergenic Diet (Unknown): low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Hypoallergenic Diet (Unknown), both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Hypoallergenic Diet (Unknown)'s report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hypoallergenic Diet (Unknown) (#624 of 2,679 by report volume); death-coded 2.6%. PlainBreed drug row · death-coded share stamp 2.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →