Drug profile

The FDA adverse-event record for Flunixin

66 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Flunixin. See the species affected, top reactions, and outcomes below.

66
adverse-event reports
22.7%
death-coded share
Horse
most-reported species
12
Colic - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
66
Total Reports
15
Deaths Reported
22.7%
Death Rate

Active Ingredients

Flunixin

Administration Routes

UnknownIntravenousIntramuscularOralParenteral

Species Affected

Horse 40
Cattle 11
Unknown 9
Dog 3
Sheep 1
Donkey 1
Pig 1

Most Affected Breeds

Quarter Horse 17
Unknown 10
Warmblood (unspecified) 4
Thoroughbred 4
Horse (unknown) 3
Holsteiner 3
Holstein-Friesian also known as Holstein 3
Simmental 3
Shepherd Dog - Australian 2
Hanovarian 2

Most Reported Reactions

Colic 12
Polyuria 11
Polydipsia 11
Other abnormal test result NOS 8
Elevated creatinine 7
Elevated blood urea nitrogen (BUN) 7
Contamination, Particulate Matter 6
Lethargy (see also Central nervous system depression in 'Neurological') 5
Depression 5
Lameness 4
Diarrhoea 4
Death 4

Outcome Breakdown

Recovered/Normal
29 (44.6%)
Died
12 (18.5%)
Ongoing
10 (15.4%)
Outcome Unknown
10 (15.4%)
Euthanized
4 (6.2%)

Flunixin Adverse Event Insights

66 reports name Flunixin; 15 recorded a death outcome (22.7% of reported events, not a population-level mortality rate). Active ingredient: Flunixin. Administration routes: Unknown, Intravenous, Intramuscular, Oral.

By species: Horse (40 reports), Cattle (11 reports), Unknown (9 reports). By breed: Quarter Horse (17), Unknown (10), Warmblood (unspecified) (4).

Leading clinical signs: Colic (12), Polyuria (11), Polydipsia (11), Other abnormal test result NOS (8). Outcome, 65 coded reports: Recovered/Normal leads at 44.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.