Drug profile

The FDA adverse-event record for Allergy Shot (Unknown)

262 FDA reports name Allergy Shot (Unknown), a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#460 of 2,679
by report volume (all drugs)
262
adverse-event reports
1.5%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Allergy Shot (Unknown) ranks #460 of 2679 by total reports (262) and #1026 of 1130 by death-coded share (1.5%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#460
This drug, reports of 2679
#1026
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Allergy Shot (Unknown) has 262 reports now versus 260 in that prior snapshot: 2 more (0.8%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Allergy Shot (Unknown) changes

Signature read: Allergy Shot (Unknown)'s 1.5% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
262
Total Reports
4
Deaths Reported
1.5%
Death-coded share of reports

Active Ingredients

Allergy Shot (Unknown)

Administration Routes

UnknownParenteralSubcutaneousOtherOral

Species Affected

Dog 246
Cat 15
Other Canids 1

Most Affected Breeds

Retriever - Labrador 22
Terrier - Yorkshire 15
Pit Bull 12
Crossbred Canine/dog 12
Shih Tzu 11
Chihuahua 10
Retriever - Golden 10
Maltese 9
Boxer (German Boxer) 8
Terrier - West Highland White 8

Most Reported Reactions

Emesis 67
Vomiting 46
Lethargy (see also Central nervous system depression in 'Neurological') 40
Lack of efficacy - NOS 26
Lack of efficacy (ectoparasite) - flea 24
Diarrhoea 17
Emesis (multiple) 11
Reddening of the skin 10
Weight loss 10
Decreased appetite 10
Behavioural disorder NOS 10
Not eating 10

Outcome Breakdown

Recovered/Normal
116 (44.3%)
Outcome Unknown
81 (30.9%)
Ongoing
39 (14.9%)
Recovered with Sequela
22 (8.4%)
Died
3 (1.1%)
Euthanized
1 (0.4%)

Allergy Shot (Unknown): low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Allergy Shot (Unknown), both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Allergy Shot (Unknown)'s report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Allergy Shot (Unknown) (#460 of 2,679 by report volume); death-coded 1.5%. PlainBreed drug row · death-coded share stamp 1.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →