Tiletamine + Zolazepam
247 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
247
Total Reports
65
Deaths Reported
2630.0%
Death Rate
Active Ingredients
TiletamineTiletamine + ZolazepamZolazepam
Administration Routes
UnknownIntramuscularIntravenousParenteralSubcutaneousVaginalOralOther
Species Affected
Cat 115
Dog 96
Unknown 33
White tailed deer 2
Buffalo 1
Most Affected Breeds
Unknown 90
Domestic Shorthair 44
Cat (unknown) 28
Retriever - Labrador 8
Domestic Mediumhair 8
Dog (unknown) 7
Domestic Longhair 4
Mixed (Dog) 3
Poodle (unspecified) 3
Shepherd Dog - German 3
Most Reported Reactions
Lack of efficacy - NOS 76
Death 28
Behavioural disorder NOS 12
Hyperactivity 12
Vomiting 11
Recovery prolonged 10
Vocalisation 10
Hyperthermia 10
Dilated pupils 10
Cardiac arrest 9
Appearance, Abnormal 9
Cyanosis 8
Outcome Breakdown
Recovered/Normal
107 (49.1%)
Euthanized
35 (16.1%)
Died
30 (13.8%)
Outcome Unknown
23 (10.6%)
Ongoing
22 (10.1%)
Recovered with Sequela
1 (0.5%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.