Afoxolaner 18.75Mg / Moxidectin 90Mcg / Pyrantel 37.5Mg Chewable Tablet
1,113 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,113
Total Reports
21
Deaths Reported
190.0%
Death Rate
Active Ingredients
Afoxolaner 18.75Mg / Moxidectin 90Mcg / Pyrantel 37.5Mg Chewable Tablet
Administration Routes
OralUnknown
Species Affected
Dog 1,025
Unknown 87
Human 1
Most Affected Breeds
Shih Tzu 103
Chihuahua 101
Unknown 89
Dog (unknown) 83
Terrier - Yorkshire 65
Dachshund (unspecified) 47
Retriever - Golden 42
Maltese 42
Beagle 40
Poodle - Miniature 36
Most Reported Reactions
Vomiting 297
Diarrhoea 128
Lethargy (see also Central nervous system depression in Neurological) 114
Lack of efficacy (endoparasite) - hookworm 92
Lack of efficacy (bacteria) - Borrelia 74
Tablets, Abnormal 65
Lack of efficacy (ectoparasite) - flea 63
Seizure NOS 57
Lack of efficacy (endoparasite) - roundworm NOS 54
Not eating 40
Itching 35
Lack of efficacy (bacteria) - Anaplasma 30
Outcome Breakdown
Outcome Unknown
526 (51.3%)
Recovered/Normal
362 (35.3%)
Ongoing
115 (11.2%)
Died
15 (1.5%)
Euthanized
6 (0.6%)
Recovered with Sequela
2 (0.2%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.