Drug profile

The FDA adverse-event record for Neomycin + Polymyxin B + Dexamethasone Ophthalmic Drops

62 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Neomycin + Polymyxin B + Dexamethasone Ophthalmic Drops. See the species affected, top reactions, and outcomes below.

62
adverse-event reports
1.6%
death-coded share
Dog
most-reported species
18
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
62
Total Reports
1
Deaths Reported
1.6%
Death Rate

Active Ingredients

Neomycin + Polymyxin B + Dexamethasone Ophthalmic Drops

Administration Routes

OphthalmicIntraocularUnknownOral

Species Affected

Dog 60
Cat 2

Most Affected Breeds

Retriever - Labrador 10
Bulldog 6
Spaniel - Cocker American 5
Bichon Frise 3
Shih Tzu 3
Pekingese 3
Pug 2
Shepherd Dog - German 2
Boxer (German Boxer) 2
Domestic Shorthair 2

Most Reported Reactions

Vomiting 18
Emesis 16
Lethargy (see also Central nervous system depression in 'Neurological') 11
Decreased appetite 4
Diarrhoea 4
Lack of efficacy - NOS 4
Behavioural disorder NOS 3
Other ear disorder NOS 3
Vocalisation 3
Scleritis 2
Seizure NOS 2
Ear infection NOS 2

Outcome Breakdown

Recovered/Normal
39 (62.9%)
Outcome Unknown
12 (19.4%)
Ongoing
8 (12.9%)
Recovered with Sequela
2 (3.2%)
Euthanized
1 (1.6%)

Neomycin + Polymyxin B + Dexamethasone Ophthalmic Drops Adverse Event Insights

62 reports name Neomycin + Polymyxin B + Dexamethasone Ophthalmic Drops; 1 recorded a death outcome (1.6% of reported events, not a population-level mortality rate). Active ingredient: Neomycin + Polymyxin B + Dexamethasone Ophthalmic Drops. Administration routes: Ophthalmic, Intraocular, Unknown, Oral.

By species: Dog (60 reports), Cat (2 reports). By breed: Retriever - Labrador (10), Bulldog (6), Spaniel - Cocker American (5).

Leading clinical signs: Vomiting (18), Emesis (16), Lethargy (see also Central nervous system depression in 'Neurological') (11), Decreased appetite (4). Outcome, 62 coded reports: Recovered/Normal leads at 62.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.