Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
29
Total Reports
6
Deaths Reported
2070.0%
Death Rate
6.4 yr
Avg Age at Report
Average weight at time of report: 36.1 kg (79.6 lbs)
Top Reported Reactions
Vomiting 7
Diarrhoea 4
Anorexia 3
Digestive tract disorder NOS 3
Death 3
Lethargy (see also Central nervous system depression in 'Neurological') 3
Decreased appetite 3
Death by euthanasia 3
Haematuria 2
Pale mucous membrane 2
Emesis 2
Lack of efficacy - NOS 2
Lack of efficacy (endoparasite) - hookworm 2
Seizure NOS 2
Panting 2
Most Referenced Drugs
Carprofen 5
Milbemycin Oxime + Spinosad 3
Lufenuron + Milbemycin Oxime 2
Ivermectin + Pyrantel As Pamoate Salt 2
Grapiprant 2
Anesthetic 2
Pyrantel Pamoate;Sarolaner 2
Glycosaminoglycan Polysulfate 1
Spinosad 1
Ivermectin 272Mcg, Pyrantel 227Mg 1
Ivermectin 136Mcg, Pyrantel Pamoate 114Mg 1
Probiotic (Unknown) 1
Selamectin 1
Fipronil, Cyphenothrin 1
Melarsomine Dihydrochloride Injection 1
Outcome Breakdown
Outcome Unknown
8 (30.8%)
Ongoing
7 (26.9%)
Recovered/Normal
4 (15.4%)
Died
3 (11.5%)
Euthanized
3 (11.5%)
Recovered with Sequela
1 (3.8%)
Gender Distribution
Female 15 (51.7%)
Male 14 (48.3%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2010 | 2 | |
| 2011 | 2 | |
| 2012 | 2 | |
| 2013 | 1 | |
| 2014 | 3 | |
| 2015 | 2 | |
| 2016 | 4 | |
| 2017 | 1 | |
| 2018 | 3 | |
| 2020 | 1 | |
| 2021 | 3 | |
| 2023 | 2 | |
| 2024 | 2 | |
| 2025 | 1 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #317 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.