Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
28
Total Reports
0
Deaths Reported
0.0%
Death Rate
4.5 yr
Avg Age at Report
Average weight at time of report: 33.9 kg (74.7 lbs)
Top Reported Reactions
Vomiting 6
Emesis 4
Lethargy (see also Central nervous system depression in 'Neurological') 3
Leucocytosis NOS 2
Swollen vulva 2
Anaemia NOS 2
Lack of efficacy - NOS 2
Behavioural disorder NOS 2
Bloody diarrhoea 2
Lack of efficacy (ectoparasite) - flea 2
Diarrhoea 2
Pruritus 2
Injection site thickening 2
Injection site pain 2
Injection site weeping (see also Skin) 2
Most Referenced Drugs
Milbemycin Oxime + Spinosad 10
No Active Ingredient Defined 6
Milbemycin Oxime + Praziquantel 5
Fluralaner 13.64% 12-Week Chew 4
Meloxicam 4
Dexmedetomidine 4
Gabapentin 3
Lotilaner 2
Imidacloprid, Flumethrin 2
Permethrin, Imidacloprid 2
Ivermectin + Pyrantel As Pamoate Salt 2
Alfaxalone 2
Maropitant 2
Butorphanol 2
Cefazolin 2
Outcome Breakdown
Ongoing
10 (35.7%)
Recovered/Normal
9 (32.1%)
Outcome Unknown
9 (32.1%)
Gender Distribution
Female 16 (57.1%)
Male 12 (42.9%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2013 | 4 | |
| 2014 | 2 | |
| 2015 | 2 | |
| 2017 | 3 | |
| 2018 | 1 | |
| 2019 | 3 | |
| 2021 | 1 | |
| 2022 | 2 | |
| 2023 | 3 | |
| 2024 | 5 | |
| 2025 | 2 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #325 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.