Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
28
Total Reports
1
Deaths Reported
360.0%
Death Rate
7.6 yr
Avg Age at Report
Average weight at time of report: 14.9 kg (32.9 lbs)
Top Reported Reactions
Vomiting 3
Emesis 3
Lack of efficacy (ectoparasite) - flea 2
Pustules 2
Rash 2
Digestive tract disorder NOS 2
Hives (see also 'Skin') 2
Loss of hearing 2
Ear discharge 2
Lethargy (see also Central nervous system depression in 'Neurological') 2
Scratching 1
Depression 1
Diarrhoea 1
Wheezing 1
Cough 1
Most Referenced Drugs
Milbemycin Oxime + Spinosad 8
Cyclosporine 2
Ivermectin + Pyrantel As Pamoate Salt 2
Afoxolaner 2
Oclacitinib Maleate 2
Pyrantel Pamoate/Praziquantel 1
Lufenuron + Milbemycin Oxime 1
Betamethasone + Florfenicol + Terbinafine 1
Cetirizine 1
Fluconazole 1
Ear Cleaner (Unknown) 1
Milbemycin Oxime, Lufenuron 1
Fluralaner Chew Tablets 1
Ivermectin + Pyrantel 1
Sarolaner 1
Outcome Breakdown
Recovered/Normal
9 (34.6%)
Outcome Unknown
7 (26.9%)
Ongoing
6 (23.1%)
Recovered with Sequela
3 (11.5%)
Died
1 (3.8%)
Gender Distribution
Male 15 (53.6%)
Female 11 (39.3%)
Unknown 2 (7.1%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2011 | 3 | |
| 2012 | 2 | |
| 2013 | 2 | |
| 2014 | 4 | |
| 2015 | 3 | |
| 2017 | 6 | |
| 2019 | 3 | |
| 2020 | 2 | |
| 2023 | 1 | |
| 2024 | 1 | |
| 2025 | 1 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #322 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.