Important: Adverse event reports are voluntarily submitted and do not prove causation. Consult your veterinarian for medical decisions about your dog.
28
Total Reports
2
Deaths Reported
710.0%
Death Rate
6.6 yr
Avg Age at Report
Average weight at time of report: 15.0 kg (33.1 lbs)
Top Reported Reactions
Vomiting 5
Emesis 4
Diarrhoea 4
Seizure NOS 3
Neutrophilia 3
Muscle spasm NOS 2
Lack of efficacy - NOS 2
Lack of efficacy (ectoparasite) - flea 2
Dilated pupils 2
Other abnormal test result NOS 2
Leucocytosis NOS 2
Anorexia 2
Lethargy (see also Central nervous system depression in 'Neurological') 2
Elevated serum alkaline phosphatase (SAP) 2
Hyperproteinaemia 2
Most Referenced Drugs
Milbemycin Oxime + Spinosad 10
Trilostane 5
Fipronil 3
Spinosad 3
Milbemycin Oxime + Praziquantel 2
Fluralaner 13.64% 12-Week Chew 2
Cyclosporine 2
Milbemycin Oxime + Lufenuron 1
Firocoxib 1
Cefpodoxime 1
Carprofen 1
Fluralaner Chew Tablets 1
Rabacfosadine Succinate 1
Capromorelin 1
Metronidazole 1
Outcome Breakdown
Recovered/Normal
10 (35.7%)
Outcome Unknown
8 (28.6%)
Ongoing
8 (28.6%)
Euthanized
2 (7.1%)
Gender Distribution
Male 16 (57.1%)
Female 12 (42.9%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2012 | 4 | |
| 2013 | 4 | |
| 2014 | 3 | |
| 2015 | 2 | |
| 2016 | 2 | |
| 2017 | 3 | |
| 2019 | 2 | |
| 2021 | 4 | |
| 2022 | 2 | |
| 2024 | 2 | |
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Rank #323 by report volume. Data reflects voluntary submissions and may not represent actual incidence rates.