Drug profile

The FDA adverse-event record for Vetmedin

149 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Vetmedin. See the species affected, top reactions, and outcomes below.

149
adverse-event reports
30.2%
death-coded share
Dog
most-reported species
24
Death by euthanasia - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
149
Total Reports
45
Deaths Reported
30.2%
Death Rate

Active Ingredients

Vetmedin

Administration Routes

OralUnknownRectal

Species Affected

Dog 143
Cat 6

Most Affected Breeds

Chihuahua 19
Terrier - Yorkshire 9
Shih Tzu 7
Spaniel (unspecified) 7
Terrier (unspecified) 6
Spaniel - King Charles Cavalier 6
Beagle 5
Retriever - Labrador 5
Retriever - Golden 4
Schnauzer - Miniature 4

Most Reported Reactions

Death by euthanasia 24
Death 21
Seizure NOS 20
Panting 18
Vomiting 17
Diarrhoea 15
Lethargy (see also Central nervous system depression in Neurological) 15
Ataxia 13
Cough 12
Not eating 12
Limb weakness 10
Elevated blood urea nitrogen (BUN) 9

Outcome Breakdown

Ongoing
71 (47.7%)
Euthanized
24 (16.1%)
Recovered/Normal
22 (14.8%)
Died
21 (14.1%)
Outcome Unknown
11 (7.4%)

Vetmedin Adverse Event Insights

149 reports name Vetmedin; 45 recorded a death outcome (30.2% of reported events, not a population-level mortality rate). Active ingredient: Vetmedin. Administration routes: Oral, Unknown, Rectal.

By species: Dog (143 reports), Cat (6 reports). By breed: Chihuahua (19), Terrier - Yorkshire (9), Shih Tzu (7).

Leading clinical signs: Death by euthanasia (24), Death (21), Seizure NOS (20), Panting (18). Outcome, 149 coded reports: Ongoing leads at 47.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.