Vitamin B

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60 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
60
Total Reports
20
Deaths Reported
3330.0%
Death Rate

Active Ingredients

Vitamin B

Administration Routes

UnknownSubcutaneousIntravenousParenteralOral

Species Affected

Dog 33
Cat 22
Cattle 3
Horse 1
Human 1

Most Affected Breeds

Domestic Shorthair 14
Retriever - Labrador 6
Chihuahua 4
Shepherd Dog - Australian 3
Cattle (unknown) 2
Mixed (Dog) 2
Unknown 2
Crossbred Canine/dog 2
Shepherd (unspecified) 2
Saint Bernard Dog 1

Most Reported Reactions

Vomiting 17
Lethargy (see also Central nervous system depression in 'Neurological') 14
Not eating 13
Anorexia 11
Death 10
Death by euthanasia 10
Leucocytosis NOS 10
Anaemia NOS 9
Diarrhoea 8
Weight loss 8
Other abnormal test result NOS 7
Elevated blood urea nitrogen (BUN) 7

Outcome Breakdown

Ongoing
22 (36.1%)
Recovered/Normal
10 (16.4%)
Died
10 (16.4%)
Euthanized
10 (16.4%)
Outcome Unknown
8 (13.1%)
Recovered with Sequela
1 (1.6%)

Data Summary

Metric Value
Total adverse event reports 60
Reports involving death 20
Case-fatality rate (reported events) 3330.0%
Distinct species in reports 5
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Vitamin B Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 60 adverse event reports referencing Vitamin B, including 20 reports in which the animal died — a 3330.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Vitamin B. Reported administration routes include Unknown, Subcutaneous, Intravenous, Parenteral. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Vitamin B reports are Dog (33 reports), Cat (22 reports), Cattle (3 reports), with Dog accounting for the largest share. Within those species, Domestic Shorthair (14), Retriever - Labrador (6), Chihuahua (4) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Vitamin B are Vomiting (17), Lethargy (see also Central nervous system depression in 'Neurological') (14), Not eating (13), Anorexia (11). Of the 61 reports with a coded outcome, Ongoing is the leading category at 36.1%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Vitamin B.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial