Drug profile

The FDA adverse-event record for Prescription Renal Diet

158 FDA reports name Prescription Renal Diet, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#610 of 2,679
by report volume (all drugs)
158
adverse-event reports
10.8%
death-coded share
Cat
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Prescription Renal Diet ranks #607 of 2679 by total reports (158) and #513 of 1130 by death-coded share (10.8%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#607
This drug, reports of 2679
#513
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Prescription Renal Diet has 158 reports now versus 152 in that prior snapshot: 6 more (3.9%).

Report change
+6
Death-coded reports
+0
Death-coded share
−0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Prescription Renal Diet changes

Signature read: 158 reports place Prescription Renal Diet in the upper third of FDA AER volume (#610 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
158
Total Reports
17
Deaths Reported
10.8%
Death-coded share of reports

Active Ingredients

Prescription Renal Diet

Administration Routes

UnknownOralSubcutaneous

Species Affected

Cat 108
Dog 50

Most Affected Breeds

Domestic Shorthair 66
Cat (unknown) 13
Domestic Longhair 11
Domestic Mediumhair 7
Shih Tzu 6
Chihuahua 4
Siamese 4
Shepherd Dog - Australian 3
Terrier (unspecified) 3
Terrier - Jack Russell 2

Most Reported Reactions

Weight loss 43
Elevated creatinine 27
Elevated blood urea nitrogen (BUN) 26
Lack of efficacy - NOS 25
Vomiting 22
Lethargy (see also Central nervous system depression in Neurological) 17
Decreased haematocrit 17
Elevated symmetrical dimethylarginine (SDMA) 16
Diarrhoea 15
Not eating 15
Death by euthanasia 15
Behavioural disorder NOS 15

Outcome Breakdown

Ongoing
66 (41.8%)
Outcome Unknown
54 (34.2%)
Recovered/Normal
21 (13.3%)
Euthanized
14 (8.9%)
Died
3 (1.9%)

Prescription Renal Diet: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Prescription Renal Diet, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Prescription Renal Diet's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Prescription Renal Diet (#610 of 2,679 by report volume); death-coded 10.8%. PlainBreed drug row · report volume stamp 158 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →