Drug profile

The FDA adverse-event record for Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost

Name: Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost - FDA Animal Adverse Event Reports
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

158 FDA reports name Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#607 of 2,679
by report volume (all drugs): 158
adverse-event reports: 82.3%
death-coded share: Cattle
most-reported species

Compiled by PlainBreed

Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost ranks #607 of 2679 by total reports (158) and #21 of 1130 by death-coded share (82.3%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1): 97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1): #607
This drug, reports of 2679: #21
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost has 158 reports now versus 158 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: −0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost changes

Signature read: Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost's 82.3% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

158

Total Reports

130

Deaths Reported

82.3%

Death-coded share of reports

Active Ingredients

Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost

Administration Routes

SubcutaneousIntramuscular

Species Affected

Cattle 158

Most Affected Breeds

Cattle (other) 84

Mixed (Cattle) 40

Holstein-Friesian also known as Holstein 18

Aberdeen Angus 9

Charolais 2

Cattle (unspecified) 1

Jersey 1

Texas Longhorn 1

Crossbred Bovine/Cattle 1

Cattle (unknown) 1

Most Reported Reactions

Death 96

Lack of efficacy (bacteria) - NOS 77

Lack of efficacy - NOS 35

CULTURE/TITER DATA ABNORMAL 19

Abnormal test result 18

Other abnormal test result NOS 18

NT - Abnormal necropsy finding NOS 16

Abnormal necropsy finding 14

Injection site swelling 13

Unrelated death 12

Sudden death 7

Myositis 7

Outcome Breakdown

Died

127 (47.6%)

Outcome Unknown

96 (36.0%)

Recovered/Normal

22 (8.2%)

Ongoing

14 (5.2%)

Euthanized

7 (2.6%)

Recovered with Sequela

1 (0.4%)

Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (158 here).

Clostridium Novyi, 8296;Clostridium Perfringens Type C, Pc8 158 Omega-3 Fatty Acids 158 Prescription Renal Diet 158 Vetmedin 158

Similar death-coded share

Nearest other drugs by death-coded share (82.3% here), distinct from the volume row.

Clostr Perf*2/Clos Others*6 Kb 82.0% Pentobarbital Sodium, Phenytoin Sodium 82.9% Clos P*2/Cl Oth*4/H.Somnus Kb 82.9% Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt 81.0%

What to do with this drug

Compare Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost's report volume and death-coded share against similar drugs nationwide. See similar drugs
Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost (#607 of 2,679 by report volume); death-coded 82.3%. PlainBreed drug row · death-coded share stamp 82.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →