Drug profile

The FDA adverse-event record for Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost

158 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost. See the species affected, top reactions, and outcomes below.

158
adverse-event reports
82.3%
death-coded share
Cattle
most-reported species
96
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
158
Total Reports
130
Deaths Reported
82.3%
Death Rate

Active Ingredients

Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost

Administration Routes

SubcutaneousIntramuscular

Species Affected

Cattle 158

Most Affected Breeds

Cattle (other) 84
Mixed (Cattle) 40
Holstein-Friesian also known as Holstein 18
Aberdeen Angus 9
Charolais 2
Cattle (unspecified) 1
Texas Longhorn 1
Jersey 1
Crossbred Bovine/Cattle 1
Cattle (unknown) 1

Most Reported Reactions

Death 96
Lack of efficacy (bacteria) - NOS 77
Lack of efficacy - NOS 35
CULTURE/TITER DATA ABNORMAL 19
Abnormal test result 18
Other abnormal test result NOS 18
NT - Abnormal necropsy finding NOS 16
Abnormal necropsy finding 14
Injection site swelling 13
Unrelated death 12
Sudden death 7
Myositis 7

Outcome Breakdown

Died
127 (47.6%)
Outcome Unknown
96 (36.0%)
Recovered/Normal
22 (8.2%)
Ongoing
14 (5.2%)
Euthanized
7 (2.6%)
Recovered with Sequela
1 (0.4%)

Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost Adverse Event Insights

158 reports name Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost; 130 recorded a death outcome (82.3% of reported events, not a population-level mortality rate). Active ingredient: Clostridium Chauvoei, Strain F, Lot No. 2-84; Clostridium Novyi, 8296, Kb; Clost. Administration routes: Subcutaneous, Intramuscular.

By species: Cattle (158 reports). By breed: Cattle (other) (84), Mixed (Cattle) (40), Holstein-Friesian also known as Holstein (18).

Leading clinical signs: Death (96), Lack of efficacy (bacteria) - NOS (77), Lack of efficacy - NOS (35), CULTURE/TITER DATA ABNORMAL (19). Outcome, 267 coded reports: Died leads at 47.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.