Drug profile

The FDA adverse-event record for Steroid

146 FDA reports name Steroid, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#643 of 2,679
by report volume (all drugs)
146
adverse-event reports
17.1%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Steroid ranks #642 of 2679 by total reports (146) and #300 of 1130 by death-coded share (17.1%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#642
This drug, reports of 2679
#300
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Steroid has 146 reports now versus 139 in that prior snapshot: 7 more (5.0%).

Report change
+7
Death-coded reports
+0
Death-coded share
−0.9 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Steroid changes

Signature read: death-coded report count at 25 is the most distinctive stamp on Steroid's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
146
Total Reports
25
Deaths Reported
17.1%
Death-coded share of reports

Active Ingredients

Steroid

Administration Routes

UnknownOralSubcutaneousTopicalIntramuscularParenteral

Species Affected

Dog 109
Cat 34
Horse 2
Ferret 1

Most Affected Breeds

Domestic Shorthair 19
Retriever - Labrador 13
Dog (unknown) 8
Chihuahua 7
Terrier - West Highland White 5
Shih Tzu 5
Crossbred Canine/dog 5
Terrier (unspecified) 4
Shepherd Dog - Australian 4
Maine Coon 4

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 24
Vomiting 22
Lack of efficacy - NOS 22
Death by euthanasia 17
Ataxia 13
INEFFECTIVE, LOSS OF EFFECT 12
Anorexia 12
Diarrhoea 11
Seizure NOS 10
Other abnormal test result NOS 9
Weight loss 9
Not eating 9

Outcome Breakdown

Ongoing
54 (37.0%)
Outcome Unknown
38 (26.0%)
Recovered/Normal
28 (19.2%)
Euthanized
17 (11.6%)
Died
8 (5.5%)
Recovered with Sequela
1 (0.7%)

Steroid: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Steroid, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (146 here).

Similar death-coded share

Nearest other drugs by death-coded share (17.1% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Steroid (#643 of 2,679 by report volume); death-coded 17.1%. PlainBreed drug row · death-coded report count stamp 25 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →