Drug profile

The FDA adverse-event record for Prednisolone Sodium Succinate

140 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Prednisolone Sodium Succinate. See the species affected, top reactions, and outcomes below.

140
adverse-event reports
17.1%
death-coded share
Unknown
most-reported species
45
Vials, Abnormal - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
140
Total Reports
24
Deaths Reported
17.1%
Death Rate

Active Ingredients

Prednisolone Sodium Succinate

Administration Routes

UnknownIntravenousIntramuscularOralSubcutaneous

Species Affected

Unknown 101
Dog 30
Cat 5
Horse 4

Most Affected Breeds

Unknown 101
Retriever - Labrador 5
Domestic Shorthair 3
Domestic (unspecified) 2
Shih Tzu 2
Terrier - Jack Russell 2
Chihuahua 2
Boxer (German Boxer) 2
Bulldog - French 2
Thoroughbred 1

Most Reported Reactions

Vials, Abnormal 45
Vials, Damaged 25
Death 18
Solution, Abnormal 11
No sign 10
Product Defect, General 9
Anaemia NOS 8
Pale mucous membrane 8
Vomiting 7
Uncoded sign 7
Leucocytosis NOS 6
Other abnormal test result NOS 6

Outcome Breakdown

Died
18 (51.4%)
Euthanized
6 (17.1%)
Ongoing
6 (17.1%)
Recovered/Normal
4 (11.4%)
Recovered with Sequela
1 (2.9%)

Prednisolone Sodium Succinate Adverse Event Insights

140 reports name Prednisolone Sodium Succinate; 24 recorded a death outcome (17.1% of reported events, not a population-level mortality rate). Active ingredient: Prednisolone Sodium Succinate. Administration routes: Unknown, Intravenous, Intramuscular, Oral.

By species: Unknown (101 reports), Dog (30 reports), Cat (5 reports). By breed: Unknown (101), Retriever - Labrador (5), Domestic Shorthair (3).

Leading clinical signs: Vials, Abnormal (45), Vials, Damaged (25), Death (18), Solution, Abnormal (11). Outcome, 35 coded reports: Died leads at 51.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.