Drug profile

The FDA adverse-event record for Potassium Chloride

146 FDA reports name Potassium Chloride, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#642 of 2,679
by report volume (all drugs)
146
adverse-event reports
48.6%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Potassium Chloride ranks #642 of 2679 by total reports (146) and #64 of 1130 by death-coded share (48.6%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#642
This drug, reports of 2679
#64
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Potassium Chloride has 146 reports now versus 141 in that prior snapshot: 5 more (3.5%).

Report change
+5
Death-coded reports
+3
Death-coded share
+0.4 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Potassium Chloride changes

Signature read: Potassium Chloride's 48.6% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
146
Total Reports
71
Deaths Reported
48.6%
Death-coded share of reports

Active Ingredients

Potassium Chloride

Administration Routes

UnknownIntravenousSubcutaneousParenteralOralOther

Species Affected

Dog 99
Cat 43
Human 2
Horse 1
Sheep 1

Most Affected Breeds

Domestic Shorthair 28
Retriever - Labrador 13
Maltese 6
Shih Tzu 6
Shepherd Dog - Australian 5
Domestic Mediumhair 5
Pointing Dog - Hungarian Short-haired (Vizsla) 5
Chihuahua 4
Unknown 3
Spaniel - King Charles Cavalier 3

Most Reported Reactions

Death by euthanasia 55
Vomiting 47
Hypokalaemia 38
Elevated alanine aminotransferase (ALT) 37
Elevated total bilirubin 34
Other abnormal test result NOS 34
Lethargy (see also Central nervous system depression in 'Neurological') 32
Dehydration 32
Not eating 32
Abnormal ultrasound finding 27
Anorexia 27
Elevated blood urea nitrogen (BUN) 24

Outcome Breakdown

Euthanized
55 (37.7%)
Ongoing
39 (26.7%)
Recovered/Normal
19 (13.0%)
Outcome Unknown
17 (11.6%)
Died
16 (11.0%)

Potassium Chloride: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Potassium Chloride, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (146 here).

Similar death-coded share

Nearest other drugs by death-coded share (48.6% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Potassium Chloride (#642 of 2,679 by report volume); death-coded 48.6%. PlainBreed drug row · death-coded share stamp 48.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →