Propofol

3,849 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

3,849

Total Reports

669

Deaths Reported

1740.0%

Death Rate

Active Ingredients

Propofol

Administration Routes

IntravenousUnknownParenteralOtherSubcutaneousIntramuscularRespiratory (Inhalation)IntrathecalOphthalmicIntraperitoneal

Species Affected

Dog 2,376

Cat 947

Unknown 489

Other 17

Human 4

Turtle 3

Pig 3

Horse 2

Rabbit 2

Other Rodents 1

Most Affected Breeds

Unknown 533

Domestic Shorthair 495

Dog (unknown) 323

Retriever - Labrador 241

Crossbred Canine/dog 133

Cat (unknown) 100

Chihuahua 90

Retriever - Golden 86

Domestic Longhair 76

Terrier - Yorkshire 74

Most Reported Reactions

Death 440

Vomiting 299

Color, Abnormal 299

Bradycardia 264

Lack of efficacy - NOS 244

Cardiac arrest 235

Lethargy (see also Central nervous system depression in 'Neurological') 204

Seizure NOS 196

Anorexia 190

Not eating 187

INEFFECTIVE, ANESTHESIA 180

Death by euthanasia 178

Outcome Breakdown

Recovered/Normal

1,133 (37.8%)

Ongoing

764 (25.5%)

Died

492 (16.4%)

Outcome Unknown

421 (14.0%)

Euthanized

177 (5.9%)

Recovered with Sequela

13 (0.4%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.