Drug profile

The FDA adverse-event record for Prazosin

65 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Prazosin. Species, reactions, and outcomes follow.

#973 of 2,679
by report volume (all drugs)
65
adverse-event reports
13.8%
death-coded share
Cat
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Prazosin ranks #970 of 2679 by total reports (65) and #405 of 1130 by death-coded share (13.8%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#970
This drug, reports of 2679
#405
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Prazosin has 65 reports now versus 60 in that prior snapshot: 5 more (8.3%).

Report change
+5
Death-coded reports
+0
Death-coded share
−1.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Prazosin changes

Signature read: death-coded report count at 9 is the most distinctive stamp on Prazosin's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
65
Total Reports
9
Deaths Reported
13.8%
Death-coded share of reports

Active Ingredients

Prazosin

Administration Routes

UnknownOral

Species Affected

Cat 57
Dog 8

Most Affected Breeds

Domestic Shorthair 40
Domestic Longhair 9
Cat (unknown) 4
Griffon - French Wire-haired Pointing 2
Domestic Mediumhair 2
Shar Pei 1
Elkhound - Norwegian Grey 1
Boxer (German Boxer) 1
American Curl Shorthair 1
Spaniel (unspecified) 1

Most Reported Reactions

Death by euthanasia 9
Not eating 9
Not urinating 6
Urinary tract infection 5
Fever 5
Seizure NOS 5
Dilated pupils 5
Behavioural disorder NOS 5
Drooling 5
Decreased appetite 5
Lethargy (see also Central nervous system depression in 'Neurological') 4
Sedation 4

Outcome Breakdown

Recovered/Normal
22 (33.8%)
Ongoing
20 (30.8%)
Outcome Unknown
14 (21.5%)
Euthanized
9 (13.8%)

Prazosin Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Prazosin, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (65 here).

Similar death-coded share

Nearest other drugs by death-coded share (13.8% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Prazosin (#973 of 2,679 by report volume); death-coded 13.8%. PlainBreed drug row · death-coded report count stamp 9 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →