Drug profile

The FDA adverse-event record for Prazosin

60 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Prazosin. See the species affected, top reactions, and outcomes below.

60
adverse-event reports
15.0%
death-coded share
Cat
most-reported species
9
Death by euthanasia - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
60
Total Reports
9
Deaths Reported
15.0%
Death Rate

Active Ingredients

Prazosin

Administration Routes

UnknownOral

Species Affected

Cat 54
Dog 6

Most Affected Breeds

Domestic Shorthair 38
Domestic Longhair 8
Cat (unknown) 4
Griffon - French Wire-haired Pointing 2
Domestic Mediumhair 2
Shar Pei 1
Elkhound - Norwegian Grey 1
Boxer (German Boxer) 1
Spaniel (unspecified) 1
American Curl Shorthair 1

Most Reported Reactions

Death by euthanasia 9
Not eating 8
Urinary tract infection 5
Fever 5
Dilated pupils 5
Not urinating 5
Drooling 5
Behavioural disorder NOS 5
Decreased appetite 5
Lethargy (see also Central nervous system depression in 'Neurological') 4
Sedation 4
Inappropriate urination 4

Outcome Breakdown

Ongoing
19 (31.7%)
Recovered/Normal
18 (30.0%)
Outcome Unknown
14 (23.3%)
Euthanized
9 (15.0%)

Prazosin Adverse Event Insights

60 reports name Prazosin; 9 recorded a death outcome (15.0% of reported events, not a population-level mortality rate). Active ingredient: Prazosin. Administration routes: Unknown, Oral.

By species: Cat (54 reports), Dog (6 reports). By breed: Domestic Shorthair (38), Domestic Longhair (8), Cat (unknown) (4).

Leading clinical signs: Death by euthanasia (9), Not eating (8), Urinary tract infection (5), Fever (5). Outcome, 60 coded reports: Ongoing leads at 31.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.