Drug profile

The FDA adverse-event record for Cerenia

63 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Cerenia. See the species affected, top reactions, and outcomes below.

63
adverse-event reports
25.4%
death-coded share
Dog
most-reported species
18
Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
63
Total Reports
16
Deaths Reported
25.4%
Death Rate

Active Ingredients

Cerenia

Administration Routes

UnknownSubcutaneousOralOther

Species Affected

Dog 52
Cat 11

Most Affected Breeds

Domestic Shorthair 7
Dog (unknown) 6
Crossbred Canine/dog 5
Schnauzer - Miniature 4
Retriever - Labrador 4
Terrier - Yorkshire 3
Boxer (German Boxer) 3
Chihuahua 3
Domestic Longhair 2
Terrier - Jack Russell 2

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 18
Vomiting 15
Emesis (multiple) 14
Other abnormal test result NOS 12
Diarrhoea 10
Abnormal radiograph finding 9
Death 8
Weight loss 7
Death by euthanasia 7
Elevated serum alkaline phosphatase (SAP) 6
Not eating 6
Bloody diarrhoea 5

Outcome Breakdown

Ongoing
20 (31.7%)
Recovered/Normal
16 (25.4%)
Outcome Unknown
10 (15.9%)
Died
9 (14.3%)
Euthanized
7 (11.1%)
Recovered with Sequela
1 (1.6%)

Cerenia Adverse Event Insights

63 reports name Cerenia; 16 recorded a death outcome (25.4% of reported events, not a population-level mortality rate). Active ingredient: Cerenia. Administration routes: Unknown, Subcutaneous, Oral, Other.

By species: Dog (52 reports), Cat (11 reports). By breed: Domestic Shorthair (7), Dog (unknown) (6), Crossbred Canine/dog (5).

Leading clinical signs: Lethargy (see also Central nervous system depression in 'Neurological') (18), Vomiting (15), Emesis (multiple) (14), Other abnormal test result NOS (12). Outcome, 63 coded reports: Ongoing leads at 31.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.