S-Adenosylmethionine And Silybin
60 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
60
Total Reports
9
Deaths Reported
1500.0%
Death Rate
Active Ingredients
S-Adenosylmethionine And Silybin
Administration Routes
OralUnknown
Species Affected
Dog 55
Cat 4
Lynx 1
Most Affected Breeds
Retriever - Labrador 8
Bichon Frise 4
Domestic Shorthair 4
Chihuahua 4
Shepherd Dog - German 4
Retriever - Golden 3
Poodle - Miniature 3
Spitz - German Pomeranian 2
Shih Tzu 2
Crossbred Canine/dog 1
Most Reported Reactions
Diarrhoea 19
Vomiting 12
Panting 8
Elevated alanine aminotransferase (ALT) 8
Seizure NOS 5
Lethargy (see also Central nervous system depression in 'Neurological') 5
Bloody diarrhoea 5
Death by euthanasia 5
Not eating 5
Weakness 4
Lack of efficacy - NOS 4
Decreased appetite 4
Outcome Breakdown
Recovered/Normal
19 (31.7%)
Ongoing
16 (26.7%)
Outcome Unknown
16 (26.7%)
Euthanized
5 (8.3%)
Died
4 (6.7%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.