Bone And Joint Support

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62 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
62
Total Reports
5
Deaths Reported
810.0%
Death Rate

Active Ingredients

Bone And Joint Support

Administration Routes

OralUnknownIntramuscular

Species Affected

Dog 57
Cat 4
Human 1

Most Affected Breeds

Retriever - Labrador 12
Retriever - Golden 4
Boxer (German Boxer) 3
Shepherd Dog - Australian 3
Shepherd Dog - German 3
Domestic Shorthair 3
Chihuahua 2
Collie - Border 2
Spitz - German Pomeranian 2
Pinscher - Miniature 2

Most Reported Reactions

Vomiting 14
Diarrhoea 7
Other abnormal test result NOS 5
Emesis 5
Death by euthanasia 5
Anaemia NOS 5
Lack of efficacy - NOS 4
Abnormal radiograph finding 4
Elevated blood urea nitrogen (BUN) 4
Lethargy (see also Central nervous system depression in 'Neurological') 3
Bone and joint disorder NOS 3
Seizure NOS 3

Outcome Breakdown

Outcome Unknown
22 (35.5%)
Ongoing
19 (30.6%)
Recovered/Normal
15 (24.2%)
Euthanized
5 (8.1%)
Recovered with Sequela
1 (1.6%)

Data Summary

Metric Value
Total adverse event reports 62
Reports involving death 5
Case-fatality rate (reported events) 810.0%
Distinct species in reports 3
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Bone And Joint Support Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 62 adverse event reports referencing Bone And Joint Support, including 5 reports in which the animal died — a 810.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Bone And Joint Support. Reported administration routes include Oral, Unknown, Intramuscular. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Bone And Joint Support reports are Dog (57 reports), Cat (4 reports), Human (1 reports), with Dog accounting for the largest share. Within those species, Retriever - Labrador (12), Retriever - Golden (4), Boxer (German Boxer) (3) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Bone And Joint Support are Vomiting (14), Diarrhoea (7), Other abnormal test result NOS (5), Emesis (5). Of the 62 reports with a coded outcome, Outcome Unknown is the leading category at 35.5%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Bone And Joint Support.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial