Drug profile

The FDA adverse-event record for Feline Leukemia Vaccine

183 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Feline Leukemia Vaccine. See the species affected, top reactions, and outcomes below.

183
adverse-event reports
13.1%
death-coded share
Cat
most-reported species
45
Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
183
Total Reports
24
Deaths Reported
13.1%
Death Rate

Active Ingredients

Feline Leukemia Vaccine

Administration Routes

UnknownSubcutaneousParenteralIntramuscularSubconjunctival

Species Affected

Cat 183

Most Affected Breeds

Domestic Shorthair 132
Domestic Longhair 18
Domestic Mediumhair 13
Siamese 7
Cat (unknown) 5
Maine Coon 3
Abyssinian cat 2
Snowshoe 2
Colorpoint Shorthair 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 45
Vomiting 25
Ataxia 23
Application site alopecia 23
Anorexia 19
Behavioural disorder NOS 19
Fever 18
Diarrhoea 16
Death 15
Other abnormal test result NOS 14
Hypersalivation 13
Hiding 13

Outcome Breakdown

Recovered/Normal
65 (35.5%)
Outcome Unknown
62 (33.9%)
Ongoing
31 (16.9%)
Died
16 (8.7%)
Euthanized
8 (4.4%)
Recovered with Sequela
1 (0.5%)

Feline Leukemia Vaccine Adverse Event Insights

183 reports name Feline Leukemia Vaccine; 24 recorded a death outcome (13.1% of reported events, not a population-level mortality rate). Active ingredient: Feline Leukemia Vaccine. Administration routes: Unknown, Subcutaneous, Parenteral, Intramuscular.

By species: Cat (183 reports). By breed: Domestic Shorthair (132), Domestic Longhair (18), Domestic Mediumhair (13).

Leading clinical signs: Lethargy (see also Central nervous system depression in 'Neurological') (45), Vomiting (25), Ataxia (23), Application site alopecia (23). Outcome, 183 coded reports: Recovered/Normal leads at 35.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.