Drug profile

The FDA adverse-event record for Clorsulon + Ivermectin

122 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Clorsulon + Ivermectin. See the species affected, top reactions, and outcomes below.

122
adverse-event reports
18.0%
death-coded share
Unknown
most-reported species
19
Containers, Abnormal - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
122
Total Reports
22
Deaths Reported
18.0%
Death Rate

Active Ingredients

ClorsulonIvermectin

Administration Routes

UnknownSubcutaneousOralParenteralAuricular (Otic)Topical

Species Affected

Unknown 67
Cattle 36
Human 5
Dog 4
Goat 3
Sheep 2
Cat 2
Alpaca 1
Pig 1
Horse 1

Most Affected Breeds

Unknown 74
Cattle (unknown) 9
Cattle (other) 9
Crossbred Bovine/Cattle 5
Aberdeen Angus 4
Nubian 3
Mixed (Cattle) 2
Sheep (other) 2
Charolais 2
Beefmaster 2

Most Reported Reactions

Containers, Abnormal 19
Death 15
Defect Unknown/Not Specified 15
Contamination NOS 13
Lack of efficacy - NOS 7
Product Defect, General 6
Death by euthanasia 5
Containers, Leaking 5
Containers, Damaged 5
Downer animal 4
Stopper, abnormal 4
Accidental exposure 4

Outcome Breakdown

Died
19 (29.7%)
Outcome Unknown
18 (28.1%)
Recovered/Normal
17 (26.6%)
Ongoing
5 (7.8%)
Euthanized
5 (7.8%)

Clorsulon + Ivermectin Adverse Event Insights

122 reports name Clorsulon + Ivermectin; 22 recorded a death outcome (18.0% of reported events, not a population-level mortality rate). Active ingredients: Clorsulon, Ivermectin. Administration routes: Unknown, Subcutaneous, Oral, Parenteral.

By species: Unknown (67 reports), Cattle (36 reports), Human (5 reports). By breed: Unknown (74), Cattle (unknown) (9), Cattle (other) (9).

Leading clinical signs: Containers, Abnormal (19), Death (15), Defect Unknown/Not Specified (15), Contamination NOS (13). Outcome, 64 coded reports: Died leads at 29.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.