Drug profile

The FDA adverse-event record for Clorsulon + Ivermectin

134 FDA reports name Clorsulon + Ivermectin, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#668 of 2,679
by report volume (all drugs)
134
adverse-event reports
18.7%
death-coded share
Unknown
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Clorsulon + Ivermectin ranks #667 of 2679 by total reports (134) and #266 of 1130 by death-coded share (18.7%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#667
This drug, reports of 2679
#266
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Clorsulon + Ivermectin has 134 reports now versus 130 in that prior snapshot: 4 more (3.1%).

Report change
+4
Death-coded reports
+1
Death-coded share
+0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Clorsulon + Ivermectin changes

Signature read: death-coded report count at 25 is the most distinctive stamp on Clorsulon + Ivermectin's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
134
Total Reports
25
Deaths Reported
18.7%
Death-coded share of reports

Active Ingredients

ClorsulonIvermectin

Administration Routes

UnknownSubcutaneousOralParenteralAuricular (Otic)Topical

Species Affected

Unknown 72
Cattle 42
Human 6
Dog 4
Goat 3
Sheep 2
Cat 2
Alpaca 1
Pig 1
Horse 1

Most Affected Breeds

Unknown 80
Cattle (unknown) 11
Cattle (other) 10
Crossbred Bovine/Cattle 5
Aberdeen Angus 5
Nubian 3
Mixed (Cattle) 2
Sheep (other) 2
Charolais 2
Beefmaster 2

Most Reported Reactions

Containers, Abnormal 19
Death 18
Defect Unknown/Not Specified 15
Contamination NOS 13
Lack of efficacy - NOS 7
Product Defect, General 6
Death by euthanasia 5
Containers, Leaking 5
Containers, Damaged 5
Downer animal 4
Stopper, abnormal 4
Accidental exposure 4

Outcome Breakdown

Died
22 (31.0%)
Outcome Unknown
20 (28.2%)
Recovered/Normal
18 (25.4%)
Ongoing
6 (8.5%)
Euthanized
5 (7.0%)

Clorsulon + Ivermectin: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Clorsulon + Ivermectin, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Clorsulon + Ivermectin's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Clorsulon + Ivermectin (#668 of 2,679 by report volume); death-coded 18.7%. PlainBreed drug row · death-coded report count stamp 25 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →