Hydrogen Peroxide

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231 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
231
Total Reports
6
Deaths Reported
260.0%
Death Rate

Active Ingredients

Hydrogen Peroxide

Administration Routes

OralUnknownTopicalOther

Species Affected

Dog 203
Cat 26
Camel 1
Human 1

Most Affected Breeds

Retriever - Labrador 26
Domestic Shorthair 16
Retriever - Golden 15
Chihuahua 12
Dog (unknown) 12
Terrier - Yorkshire 10
Shepherd Dog - Australian 9
Shepherd Dog - German 8
Pit Bull 7
Siberian Husky 6

Most Reported Reactions

Vomiting 107
Accidental exposure 53
Overdose 50
Lethargy (see also Central nervous system depression in 'Neurological') 27
Emesis 22
Lethargy (see also Central nervous system depression in Neurological) 14
Diarrhoea 13
Emesis (multiple) 12
Seizure NOS 8
Not eating 8
Behavioural disorder NOS 7
Elevated alanine aminotransferase (ALT) 7

Outcome Breakdown

Recovered/Normal
116 (50.0%)
Outcome Unknown
55 (23.7%)
Ongoing
53 (22.8%)
Euthanized
3 (1.3%)
Died
3 (1.3%)
Recovered with Sequela
2 (0.9%)

Data Summary

Metric Value
Total adverse event reports 231
Reports involving death 6
Case-fatality rate (reported events) 260.0%
Distinct species in reports 4
Distinct breeds in reports 20
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Hydrogen Peroxide Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 231 adverse event reports referencing Hydrogen Peroxide, including 6 reports in which the animal died — a 260.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Hydrogen Peroxide. Reported administration routes include Oral, Unknown, Topical, Other. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Hydrogen Peroxide reports are Dog (203 reports), Cat (26 reports), Camel (1 reports), with Dog accounting for the largest share. Within those species, Retriever - Labrador (26), Domestic Shorthair (16), Retriever - Golden (15) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Hydrogen Peroxide are Vomiting (107), Accidental exposure (53), Overdose (50), Lethargy (see also Central nervous system depression in 'Neurological') (27). Of the 232 reports with a coded outcome, Recovered/Normal is the leading category at 50.0%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Hydrogen Peroxide.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial