Drug profile

The FDA adverse-event record for Hydrogen Peroxide

231 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Hydrogen Peroxide. See the species affected, top reactions, and outcomes below.

231
adverse-event reports
2.6%
death-coded share
Dog
most-reported species
107
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
231
Total Reports
6
Deaths Reported
2.6%
Death Rate

Active Ingredients

Hydrogen Peroxide

Administration Routes

OralUnknownTopicalOther

Species Affected

Dog 203
Cat 26
Camel 1
Human 1

Most Affected Breeds

Retriever - Labrador 26
Domestic Shorthair 16
Retriever - Golden 15
Chihuahua 12
Dog (unknown) 12
Terrier - Yorkshire 10
Shepherd Dog - Australian 9
Shepherd Dog - German 8
Pit Bull 7
Siberian Husky 6

Most Reported Reactions

Vomiting 107
Accidental exposure 53
Overdose 50
Lethargy (see also Central nervous system depression in 'Neurological') 27
Emesis 22
Lethargy (see also Central nervous system depression in Neurological) 14
Diarrhoea 13
Emesis (multiple) 12
Seizure NOS 8
Not eating 8
Behavioural disorder NOS 7
Elevated alanine aminotransferase (ALT) 7

Outcome Breakdown

Recovered/Normal
116 (50.0%)
Outcome Unknown
55 (23.7%)
Ongoing
53 (22.8%)
Euthanized
3 (1.3%)
Died
3 (1.3%)
Recovered with Sequela
2 (0.9%)

Hydrogen Peroxide Adverse Event Insights

231 reports name Hydrogen Peroxide; 6 recorded a death outcome (2.6% of reported events, not a population-level mortality rate). Active ingredient: Hydrogen Peroxide. Administration routes: Oral, Unknown, Topical, Other.

By species: Dog (203 reports), Cat (26 reports), Camel (1 reports). By breed: Retriever - Labrador (26), Domestic Shorthair (16), Retriever - Golden (15).

Leading clinical signs: Vomiting (107), Accidental exposure (53), Overdose (50), Lethargy (see also Central nervous system depression in 'Neurological') (27). Outcome, 232 coded reports: Recovered/Normal leads at 50.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.