Drug profile

The FDA adverse-event record for Hydrogen Peroxide

236 FDA reports name Hydrogen Peroxide, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#495 of 2,679
by report volume (all drugs)
236
adverse-event reports
2.5%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Hydrogen Peroxide ranks #495 of 2679 by total reports (236) and #950 of 1130 by death-coded share (2.5%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#495
This drug, reports of 2679
#950
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hydrogen Peroxide has 236 reports now versus 234 in that prior snapshot: 2 more (0.9%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hydrogen Peroxide changes

Signature read: 236 reports place Hydrogen Peroxide in the upper third of FDA AER volume (#495 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
236
Total Reports
6
Deaths Reported
2.5%
Death-coded share of reports

Active Ingredients

Hydrogen Peroxide

Administration Routes

OralUnknownTopicalOther

Species Affected

Dog 208
Cat 26
Camel 1
Human 1

Most Affected Breeds

Retriever - Labrador 26
Domestic Shorthair 16
Retriever - Golden 15
Chihuahua 13
Dog (unknown) 12
Terrier - Yorkshire 10
Shepherd Dog - German 9
Shepherd Dog - Australian 9
Pit Bull 7
Shih Tzu 6

Most Reported Reactions

Vomiting 109
Accidental exposure 57
Overdose 51
Lethargy (see also Central nervous system depression in 'Neurological') 27
Emesis 22
Lethargy (see also Central nervous system depression in Neurological) 15
Diarrhoea 13
Emesis (multiple) 13
Seizure NOS 8
Not eating 8
Behavioural disorder NOS 7
Elevated alanine aminotransferase (ALT) 7

Outcome Breakdown

Recovered/Normal
119 (50.2%)
Ongoing
55 (23.2%)
Outcome Unknown
55 (23.2%)
Euthanized
3 (1.3%)
Died
3 (1.3%)
Recovered with Sequela
2 (0.8%)

Hydrogen Peroxide: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Hydrogen Peroxide, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hydrogen Peroxide (#495 of 2,679 by report volume); death-coded 2.5%. PlainBreed drug row · report volume stamp 236 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →