Drug profile

The FDA adverse-event record for Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt

237 FDA reports name Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#494 of 2,679
by report volume (all drugs)
237
adverse-event reports
81.0%
death-coded share
Cattle
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt ranks #493 of 2679 by total reports (237) and #23 of 1130 by death-coded share (81.0%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#493
This drug, reports of 2679
#23
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt has 237 reports now versus 237 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt changes

Signature read: Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt's 81.0% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
237
Total Reports
192
Deaths Reported
81.0%
Death-coded share of reports

Active Ingredients

Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt

Administration Routes

SubcutaneousIntramuscularUnknown

Species Affected

Cattle 234
Unknown 3

Most Affected Breeds

Cattle (other) 143
Mixed (Cattle) 30
Holstein-Friesian also known as Holstein 21
Aberdeen Angus 14
Crossbred Bovine/Cattle 13
Hereford cattle 3
Cattle (unspecified) 3
Cattle (unknown) 3
Unknown 3
Gelbvieh 1

Most Reported Reactions

Lack of efficacy (bacteria) - NOS 162
Death 140
Lack of efficacy - NOS 43
CULTURE/TITER DATA ABNORMAL 25
Other abnormal test result NOS 23
Abnormal test result 21
Increased mortality rate 18
PR-LUNG(S), LESION(S) 14
Abnormal necropsy finding 14
NT - Abnormal necropsy finding NOS 14
NT - fibrinous (broncho) pneumonia/fibrinous pleuropneumonia 12
DEATH-TREATMENT FAILURE 8

Outcome Breakdown

Died
192 (47.8%)
Outcome Unknown
147 (36.6%)
Recovered/Normal
26 (6.5%)
Ongoing
23 (5.7%)
Recovered with Sequela
10 (2.5%)
Euthanized
4 (1.0%)

Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt (#494 of 2,679 by report volume); death-coded 81.0%. PlainBreed drug row · death-coded share stamp 81.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →