Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt

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237 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
237
Total Reports
192
Deaths Reported
8100.0%
Death Rate

Active Ingredients

Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt

Administration Routes

SubcutaneousIntramuscularUnknown

Species Affected

Cattle 234
Unknown 3

Most Affected Breeds

Cattle (other) 143
Mixed (Cattle) 30
Holstein-Friesian also known as Holstein 21
Aberdeen Angus 14
Crossbred Bovine/Cattle 13
Hereford cattle 3
Cattle (unspecified) 3
Cattle (unknown) 3
Unknown 3
Gelbvieh 1

Most Reported Reactions

Lack of efficacy (bacteria) - NOS 162
Death 140
Lack of efficacy - NOS 43
CULTURE/TITER DATA ABNORMAL 25
Other abnormal test result NOS 23
Abnormal test result 21
Increased mortality rate 18
PR-LUNG(S), LESION(S) 14
Abnormal necropsy finding 14
NT - Abnormal necropsy finding NOS 14
NT - fibrinous (broncho) pneumonia/fibrinous pleuropneumonia 12
DEATH-TREATMENT FAILURE 8

Outcome Breakdown

Died
192 (47.8%)
Outcome Unknown
147 (36.6%)
Recovered/Normal
26 (6.5%)
Ongoing
23 (5.7%)
Recovered with Sequela
10 (2.5%)
Euthanized
4 (1.0%)

Data Summary

Metric Value
Total adverse event reports 237
Reports involving death 192
Case-fatality rate (reported events) 8100.0%
Distinct species in reports 2
Distinct breeds in reports 13
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 237 adverse event reports referencing Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt, including 192 reports in which the animal died — a 8100.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt. Reported administration routes include Subcutaneous, Intramuscular, Unknown. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt reports are Cattle (234 reports), Unknown (3 reports), with Cattle accounting for the largest share. Within those species, Cattle (other) (143), Mixed (Cattle) (30), Holstein-Friesian also known as Holstein (21) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt are Lack of efficacy (bacteria) - NOS (162), Death (140), Lack of efficacy - NOS (43), CULTURE/TITER DATA ABNORMAL (25). Of the 402 reports with a coded outcome, Died is the leading category at 47.8%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial